ReviewClinical & translational immunology2017
Embracing the gut microbiota: the new frontier for inflammatory and infectious diseases.
Review in Clinical & translational immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06606951 (Effect Of Probiotics Supplementation on Outcome Of Malnourished Children Admitted at Assiut University Children's Hospital), which is not on this map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect Of Probiotics Supplementation on Outcome Of Malnourished Children Admitted at Assiut University Children's Hospital
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it, 126 citations in OpenAlex.
- Assessing the long-term effects of microbial therapeutics as treatment within psychiatry: a systematic review.Frontiers in psychiatry · 2025Pooled it
- Distribution of schistosomes and soil-transmitted helminth infections and their association with growth and nutritional status of School-aged children of the Matta health area in the West region of Cameroon.PLoS neglected tropical diseases · 2025Article
- Article
- Quantifying intraspecific variation in host resistance and tolerance to a lethal pathogen.The Journal of animal ecology · 2025Article
- The forgotten link: how the oral microbiome shapes childhood growth and development.Frontiers in oral health · 2025Review
- The role of gut microbial β-glucuronidases in carcinogenesis and cancer treatment: a scoping review.Journal of cancer research and clinical oncology · 2024Article
- Imbalance of intestinal flora activates inflammatory response contributing to acute lung injury.Journal of thoracic disease · 2024Article
- The Future Exploring of Gut Microbiome-Immunity Interactions: From In Vivo/Vitro Models to In Silico Innovations.Microorganisms · 2024Review
- A long journey to the colon: The role of the small intestine microbiota in intestinal disease.Molecular microbiology · 2024Review
- Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases.Journal of personalized medicine · 2024Review
- Characteristics of gut microbiota in patients with asthenozoospermia: a Chinese pilot study.BMC microbiology · 2024Article
- Mitigation effects of plant carbon black on intestinal morphology, inflammation, antioxidant status, and microbiota in piglets challenged with deoxynivalenol.Frontiers in immunology · 2024Article
- Gut microbes improve prognosis ofFrontiers in cellular and infection microbiology · 2024Article
- The Debate between the Human Microbiota and Immune System in Treating Aerodigestive and Digestive Tract Cancers: A Review.Vaccines · 2023Review
- Inosine Pretreatment Attenuates LPS-Induced Lung Injury through Regulating the TLR4/MyD88/NF-κB Signaling Pathway In Vivo.Nutrients · 2022Article
- Nutrigenomics and Nutrigenetics Research in New Zealand, and Its Relevance and Application to Gastrointestinal Health.Nutrients · 2022Review
- Gut microbiota profile of COVID-19 patients: Prognosis and risk stratification (MicroCOVID-19 study).Frontiers in microbiology · 2022Article
- Article
- Colonization resistance: metabolic warfare as a strategy against pathogenic Enterobacteriaceae.Current opinion in microbiology · 2021Review
- Malnutrition and Gut Microbiota in Children.Nutrients · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gut microbiota provides essential signals for the development and appropriate function of the immune system. Through this critical contribution to immune fitness, the gut microbiota has a key role in health and disease. Recent advances in the technological applications to study microbial communities and their functions have contributed to a rapid increase in host-microbiota research. Although it still remains difficult to define a so-called 'normal' or 'healthy' microbial composition, alterations in the gut microbiota have been shown to influence the susceptibility of the host to different diseases. Current translational research combined with recent technological and computational advances have enabled in-depth study of the link between microbial composition and immune function, addressing the interplay between the gut microbiota and immune responses. As such, beneficial modulation of the gut microbiota is a promising clinical target for many prevalent diseases including inflammatory bowel disease, metabolic abnormalities such as obesity, reduced insulin sensitivity and low-grade inflammation, allergy and protective immunity against infections.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.