Evidence map›Paper›PMID 28197288›Full record

ArticleCardiology research2016

Serum Triglyceride Lowering Effect of Cilnidipine in Patients With Essential Hypertension.

Prakash Kumar, Arijit Das, Satish Chandra, Manju Gari, U S P Keshri, Kusum Kumari

Open access · diamondAbstract read
In one paragraph

Article in Cardiology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. RSSDI Guidelines for the management of hypertension in patients with diabetes mellitus.International journal of diabetes in developing countries · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Prakash KumarDepartment of Cardiology, Rajendra Institute of Medical Sciences (RIMS), Ranchi, India.
Arijit DasDepartment of Pharmacology, Rajendra Institute of Medical Sciences (RIMS), Ranchi, India.
Satish ChandraDepartment of Pharmacology, Rajendra Institute of Medical Sciences (RIMS), Ranchi, India.
Manju GariDepartment of Pharmacology, Rajendra Institute of Medical Sciences (RIMS), Ranchi, India.
U S P KeshriDepartment of Pharmacology, Rajendra Institute of Medical Sciences (RIMS), Ranchi, India.
Kusum KumariDepartment of Pharmacology, Rajendra Institute of Medical Sciences (RIMS), Ranchi, India.
Rajendra Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany epidemiological studies have established the relationship between hypertension and dyslipidemia. Calcium channel blockers (CCBs) are one of the first-line drugs for newly diagnosed patients with essential hypertension. Cilnidipine as a newer CCB acting by blocking both L- and N-type calcium channels possesses additional beneficial effects apart from lowering blood pressure (BP). The aim of this study was to evaluate the effectiveness of cilnidipine in patients with essential hypertension with borderline dyslipidemia and its effects on lipid profile.

methodsOut of 45 enrolled patients, who fulfilled the inclusion criteria, only 37 completed the study. Cilnidipine was started at 10 mg/day, and then adjusted to 5 - 20 mg/day to achieve the target blood pressure.

resultsAfter 12 weeks of study, patients showed significant reduction in systolic blood pressure, diastolic blood pressure, mean BP, heart rate and serum triglyceride level from baseline values (P < 0.00).

conclusionIn clinical setting where both hypertension and hypertriglyceridemia exist, cilnidipine can be a promising drug of choice.

Indexed as

CilnidipineDyslipidemiaHeart rateHypertensionHypertriglyceridemiaL- and N-type calcium channel blocker

Identifiers

PMID28197288
PMCPMC5295564
OpenAlexW2547503290

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.