Evidence map›Paper›PMID 28196881›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Engineered holocytochrome

Deanna L Mendez, Shalon E Babbitt, Jeremy D King, John D'Alessandro, Michael B Watson, Robert E Blankenship, Liviu M Mirica, Robert G Kranz

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. A Divergent CytochromebioRxiv : the preprint server for biology · 2025
    Article
  4. Biogenesis of CytochromesACS infectious diseases · 2025
    Article
  5. Article
  6. Biogenesis of cytochromesbioRxiv : the preprint server for biology · 2024
    Article
  7. Article
  8. Article
  9. Recombinant Biogenesis and Analysis of Cytochrome c Species.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  10. Article
  11. Direct tests of cytochromeProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Deanna L MendezDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.
Shalon E BabbittDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.
Jeremy D KingDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.
John D'AlessandroDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.
Michael B WatsonDepartment of Chemistry, Washington University in St. Louis, St. Louis, MO 63130.
Robert E BlankenshipDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.
Liviu M MiricaDepartment of Chemistry, Washington University in St. Louis, St. Louis, MO 63130.
Robert G KranzDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130; kranz@wustl.edu.
Washington University in St. Louis · US

Funding

MOLECULAR GENETIC ANALYSES OF CYTOCHROMES C BIOGENESISR01GM047909 · NIGMS · WASHINGTON UNIVERSITY · PI KRANZ, ROBERT G. · 1994 to 2019
$6.0M
PROBING THE ACTIVE SITE OF THE MITOCHONDRIAL HOLOCYTOCHROME C SYNTHASE, HCCSF32GM108278 · NIGMS · WASHINGTON UNIVERSITY · PI LEDBETTER, SHALON ELIZABETH · 2014 to 2016
$135k
NIGMS NIH HHS F32 GM108278NIGMS NIH HHS R01 GM047909
6 · The paper itself

Abstract

Cytochrome

Indexed as

Amino Acid MotifsAmino Acid SubstitutionCatalytic DomainCloning, MolecularCoenzymesCytochromes cElectron TransportEscherichia coliGene ExpressionHemeHumansLyasesMutationOxidation-ReductionProtein BindingProtein EngineeringCoenzymescytochrome C synthetaseCytochromes cHemeLyasesRecombinant Proteinsaxial ligandscytochrome cHCCShemespectroscopy

Identifiers

PMID28196881
PMCPMC5338485
OpenAlexW2588839330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.