Evidence map›Paper›PMID 28196836›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2017

Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival

Dorathy-Ann Harris, Ji-Min Park, Kyung-Soon Lee, Cong Xu, Nephi Stella, Chris Hague

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. βCells · 2024
    Article
  2. Review
  3. Article
  4. N-glycosylation of αScientific reports · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dorathy-Ann HarrisDepartments of Pharmacology (D.-A.H., J.-M.P., K.-S.L., C.X., N.S., C.H.) and Psychiatry and Behavioral Sciences (C.X., N.S.), University of Washington School of Medicine, Seattle, Washington.
Ji-Min ParkDepartments of Pharmacology (D.-A.H., J.-M.P., K.-S.L., C.X., N.S., C.H.) and Psychiatry and Behavioral Sciences (C.X., N.S.), University of Washington School of Medicine, Seattle, Washington.
Kyung-Soon LeeDepartments of Pharmacology (D.-A.H., J.-M.P., K.-S.L., C.X., N.S., C.H.) and Psychiatry and Behavioral Sciences (C.X., N.S.), University of Washington School of Medicine, Seattle, Washington.
Cong XuDepartments of Pharmacology (D.-A.H., J.-M.P., K.-S.L., C.X., N.S., C.H.) and Psychiatry and Behavioral Sciences (C.X., N.S.), University of Washington School of Medicine, Seattle, Washington.
Nephi StellaDepartments of Pharmacology (D.-A.H., J.-M.P., K.-S.L., C.X., N.S., C.H.) and Psychiatry and Behavioral Sciences (C.X., N.S.), University of Washington School of Medicine, Seattle, Washington.
Chris HagueDepartments of Pharmacology (D.-A.H., J.-M.P., K.-S.L., C.X., N.S., C.H.) and Psychiatry and Behavioral Sciences (C.X., N.S.), University of Washington School of Medicine, Seattle, Washington chague@uw.edu.
University of Washington · US

Funding

Pharmacological Sciences SupplementT32GM007750 · NIGMS · UNIVERSITY OF WASHINGTON · PI ATKINS, WILLIAM M · 1985 to 2023
$12.6M
Cannabinoid Signaling System in Microglial CellsR01DA014486 · NIDA · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI · 2001 to 2016
$4.2M
The a-catulin/dystrophin-associated protein complex regulates GPCR function.R01GM100893 · NIGMS · UNIVERSITY OF WASHINGTON · PI HAGUE, CHRIS S · 2012 to 2020
$2.9M
NIDA NIH HHS R01 DA014486NIGMS NIH HHS R01 GM100893
6 · The paper itself

Abstract

Small molecules that target the adrenergic family of G protein-coupled receptors (GPCRs) show promising therapeutic efficacy for the treatment of various cancers. In this study, we report that human colon cancer cell line SW480 expresses low-density functional

Indexed as

CarcinomaColonic NeoplasmsReceptors, Adrenergic, alpha-1Adrenergic alpha-1 Receptor AntagonistsBiopharmaceuticsCell Line, TumorCell ProliferationCell SurvivalDrug DiscoveryHumansReceptors, G-Protein-CoupledStimulation, ChemicalAdrenergic alpha-1 Receptor AntagonistsReceptors, Adrenergic, alpha-1Receptors, G-Protein-Coupled

Identifiers

PMID28196836
PMCPMC5399639
OpenAlexW2588159941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.