Evidence map›Paper›PMID 28196524›Full record

ArticleBMC medicine2017

Financial barriers and adverse clinical outcomes among patients with cardiovascular-related chronic diseases: a cohort study.

David J T Campbell, Braden J Manns, Robert G Weaver, Brenda R Hemmelgarn, Kathryn M King-Shier, Claudia Sanmartin

Abstract read
In one paragraph

Article in BMC medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Exploring patient and pharmacist perspectives on complex interventions for cardiovascular prevention: A qualitative descriptive process evaluation.Health expectations : an international journal of public participation in health care and health policy · 2020
    Trial
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  5. Social determinants of health and hospitalization risk in heart failure: A Retrospective analysis.American heart journal plus : cardiology research and practice · 2026
    Article
  6. Review
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  13. Patients' and Nurses' Perceptions of Diabetes Self-Management in Oman: A Qualitative Study.International journal of environmental research and public health · 2022
    Article
  14. Article
  15. Variables Determining Higher Home Care Effectiveness in Patients with Chronic Cardiovascular Disease.International journal of environmental research and public health · 2022
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David J T CampbellDepartment of Medicine, Cumming School of Medicine, University of Calgary, Health Sciences Centre, Room G236, 3330 Hospital Dr NW, Calgary, AB, T2N 4N1, Canada. dcampbel@ucalgary.ca.
Braden J MannsDepartment of Medicine, Cumming School of Medicine, University of Calgary, Health Sciences Centre, Room G236, 3330 Hospital Dr NW, Calgary, AB, T2N 4N1, Canada.
Robert G WeaverDepartment of Medicine, Cumming School of Medicine, University of Calgary, Health Sciences Centre, Room G236, 3330 Hospital Dr NW, Calgary, AB, T2N 4N1, Canada.
Brenda R HemmelgarnDepartment of Medicine, Cumming School of Medicine, University of Calgary, Health Sciences Centre, Room G236, 3330 Hospital Dr NW, Calgary, AB, T2N 4N1, Canada.
Kathryn M King-ShierDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Claudia SanmartinDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

Funding

CIHR
6 · The paper itself

Abstract

backgroundSome patients with cardiovascular-related chronic diseases such as diabetes and heart disease report financial barriers to achieving optimal health. Previous surveys report that the perception of having a financial barrier is associated with self-reported adverse clinical outcomes. We sought to confirm these findings using linked survey and administrative data to determine, among patients with cardiovascular-related chronic diseases, if there is an association between perceived financial barriers and the outcomes of: (1) disease-related hospitalizations, (2) all-cause mortality and (3) inpatient healthcare costs.

methodsWe used ten cycles of the nationally representative Canadian Community Health Survey (administered between 2000 and 2011) to identify a cohort of adults aged 45 and older with hypertension, diabetes, heart disease or stroke. Perceived financial barriers to various aspects of chronic disease care and self-management were identified (including medications, healthful food and home care) from the survey questions, using similar questions to those used in previous studies. The cohort was linked to administrative data sources for outcome ascertainment (Discharge Abstract Database, Canadian Mortality Database, Patient Cost Estimator). We utilized Poisson regression techniques, adjusting for potential confounding variables (age, sex, education, multimorbidity, smoking status), to assess for associations between perceived financial barriers and disease-related hospitalization and all-cause mortality. We used gross costing methodology and a variety of modelling approaches to assess the impact of financial barriers on hospital costs.

resultsWe identified a cohort of 120,752 individuals over the age of 45 years with one or more of the following: hypertension, diabetes, heart disease or stroke. One in ten experienced financial barriers to at least one aspect of their care, with the two most common being financial barriers to accessing medications and healthful food. Even after adjustment, those with at least one financial barrier had an increased rate of disease-related hospitalization and mortality compared to those without financial barriers with adjusted incidence rate ratios of 1.36 (95% CI: 1.29-1.44) and 1.24 (1.16-1.32), respectively. Furthermore, having a financial barrier to care was associated with 30% higher inpatient costs compared to those without financial barriers. DISCUSSION: This study, using novel linked national survey and administrative data, demonstrates that chronic disease patients with perceived financial barriers have worse outcomes and higher resource utilization, corroborating the findings from prior self-report studies. The overall exposure remained associated with the primary outcome even in spite of adjustment for income. This suggests that a patient's perception of a financial barrier might be used in clinical and research settings as an additional measure along with standard measures of socioeconomic status (ie. income, education, social status).

conclusionsAfter adjusting for relevant covariates, perceiving a financial barrier was associated with increased rates of hospitalization and mortality and higher hospital costs compared to those without financial barriers. The demonstrable association with adverse outcomes and increased costs seen in this study may provide an impetus for policymakers to seek to invest in interventions which minimize the impact of financial barriers.

Indexed as

AgedCanadaCardiovascular DiseasesChronic DiseaseCohort StudiesFemaleHealth Care CostsHumansMaleMiddle AgedTreatment Outcome

Identifiers

PMID28196524
PMCPMC5309998

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.