ArticleTranslational psychiatry2017
BDNF val66met association with serotonin transporter binding in healthy humans.
Article in Translational psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05450822 (The BrainDrugs-Epilepsy Study), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cerebral serotonin transporter measurements with [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Pooled it
- Brain-Derived Neurotropic FactorBioMed research international · 2017Trial
- No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state.Clinical epigenetics · 2024Article
- Physical Exercise as an Intervention for Depression: Evidence for Efficacy and Mu-Opioid Receptors as a Mechanism of Action.Advances in neurobiology · 2024Review
- The BrainDrugs-epilepsy study: A prospective open-label cohort precision medicine study in epilepsy.Neuroscience applied · 2023Article
- Genetic polymorphisms iniScience · 2022Article
- Brain serotonin transporter is associated with cognitive-affective biases in healthy individuals.Human brain mapping · 2022Article
- Common HTR2A variants and 5-HTTLPR are not associated with human in vivo serotonin 2A receptor levels.Human brain mapping · 2020Article
- Oral contraceptives and the serotonin 4 receptor: a molecular brain imaging study in healthy women.Acta psychiatrica Scandinavica · 2020Article
- Effects of Vortioxetine on depression model rats and expression of BDNF and Trk B in hippocampus.Experimental and therapeutic medicine · 2020Article
- High-resolution PET imaging reveals subtle impairment of the serotonin transporter in an early non-depressed Parkinson's disease cohort.European journal of nuclear medicine and molecular imaging · 2020Article
- Predicting Treatment Outcome in Major Depressive Disorder Using Serotonin 4 Receptor PET Brain Imaging, Functional MRI, Cognitive-, EEG-Based, and Peripheral Biomarkers: A NeuroPharm Open Label Clinical Trial Protocol.Frontiers in psychiatry · 2020Article
- Serotonin Receptor 1A Variation Is Associated with Anxiety and Agonistic Behavior in Chimpanzees.Molecular biology and evolution · 2019Article
- Genetics of stroke recovery: BDNF val66met polymorphism in stroke recovery and its interaction with aging.Neurobiology of disease · 2019Review
- Epistasis of HTR1A and BDNF risk genes alters cortical 5-HT1A receptor binding: PET results link genotype to molecular phenotype in depression.Translational psychiatry · 2019Article
- Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age.Frontiers in psychology · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The serotonin transporter (5-HTT) is a key feature of the serotonin system, which is involved in behavior, cognition and personality and implicated in neuropsychiatric illnesses including depression. The brain-derived neurotrophic factor (BDNF) val66met and 5-HTTLPR polymorphisms have predicted differences in 5-HTT levels in humans but with equivocal results, possibly due to limited sample sizes. Within the current study we evaluated these genetic predictors of 5-HTT binding with [
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