ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018
Diagnostic performance of the quantification of myocardium at risk from MPI SPECT/CTA 2G fusion for detecting obstructive coronary disease: A multicenter trial.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Quantitative clinical nuclear cardiology, part 2: Evolving/emerging applications.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Review
- Vessel-specific quantification of absolute myocardial blood flow, myocardial flow reserve and relative flow reserve by means of fused dynamicJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Multimodality image fusion, moving forward.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Rationale and design of the quantification of myocardial blood flow using dynamic PET/CTA-fused imagery (DEMYSTIFY) to determine physiological significance of specific coronary lesions.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Observational
- Hybrid imaging and publishing.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2018. Part 1 of 2: Positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Review
- Hybrid quantitative imaging: Will it enter clinical practice?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Multimodality Image Fusion for Coronary Artery Disease Detection: Concepts and Latest Developments.Annals of nuclear cardiology · 2018Article
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundThe effective non-invasive identification of coronary artery disease (CAD) and its proper referral for invasive treatment are still unresolved issues. We evaluated our quantification of myocardium at risk (MAR) from our second generation 3D MPI/CTA fusion framework for the detection and localization of obstructive coronary disease.
methodsStudies from 48 patients who had rest/stress MPI, CTA, and ICA were analyzed from 3 different institutions. From the CTA, a 3D biventricular surface of the myocardium with superimposed coronaries was extracted and fused to the perfusion distribution. Significant lesions were identified from CTA readings and positioned on the fused display. Three estimates of MAR were computed on the 3D LV surface on the basis of the MPI alone (MAR
resultsAreas under the ROC curve (AUC) for CAD detection using MAR
conclusionsUsing ICA as the reference standard, MAR as the quantitative parameter, and AUC to measure diagnostic performance, MPI-CTA fusion imaging provided incremental diagnostic information compared to MPI or CTA alone for the diagnosis and localization of CAD.
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