ArticlePediatric nephrology (Berlin, Germany)2017
Outcome of extremely low birth weight infants with a history of neonatal acute kidney injury.
Article in Pediatric nephrology (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Acute kidney injury magnitude, mortality, and associated factors among neonates in sub-Saharan Africa: a systematic review and meta-analysis.Pediatric nephrology (Berlin, Germany) · 2025Pooled it
- Acute kidney injury in premature and low birth weight neonates: a systematic review and meta-analysis.Pediatric nephrology (Berlin, Germany) · 2022Pooled it
- Pooled it
- Kidney health and blood pressure after very preterm birth: a cohort study at school age.Pediatric nephrology (Berlin, Germany) · 2026Article
- Multidisciplinary neonatal acute kidney injury provider perceptions and practice patterns.Pediatric nephrology (Berlin, Germany) · 2026Article
- Early lactate elimination trend during therapeutic hypothermia predicts acute kidney injury in hypoxic ischemic encephalopathy.Pediatric nephrology (Berlin, Germany) · 2026Article
- Kidney care at NICU discharge and follow-up recommendations for preterm infants<34 weeks.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Urotensin II system contributes to ischemic acute kidney injury in neonatal pigs.Renal failure · 2025Article
- Kidney Health Monitoring in Neonatal Intensive Care Unit Graduates: A Modified Delphi Consensus Statement.JAMA network open · 2024Article
- Adolescent Kidney Outcomes after Extremely Preterm Birth and Neonatal Acute Kidney Injury: There May be More to the Story.American journal of perinatology · 2024Article
- Neurodevelopment After Neonatal Acute Kidney Injury in Very Preterm-Birth Children.Kidney international reports · 2023Article
- Prognosis and clinical issues of esophageal atresia in extremely low birth weight neonates: a case series.BMC pediatrics · 2023Article
- Kidney outcomes in early adolescence following perinatal asphyxia and hypothermia-treated hypoxic-ischaemic encephalopathy.Pediatric nephrology (Berlin, Germany) · 2023Article
- Impact of nephrotoxic drugs on urinary biomarkers of renal function in very preterm infants.Pediatric research · 2022Observational
- Long-term follow-up of patients after acute kidney injury in the neonatal period: abnormal ambulatory blood pressure findings.BMC nephrology · 2022Article
- Clinical course of neonatal acute kidney injury: multi-center prospective cohort study.BMC pediatrics · 2022Article
- Improving the identification of acute kidney injury in the neonatal ICU: three centers' experiences.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- Association between Elevated Urine Neutrophil Gelatinase-Associated Lipocalin and Postoperative Acute Kidney Injury in Neonates.The Journal of pediatrics · 2021Observational
- Neonatal acute kidney injury: a case-based approach.Pediatric nephrology (Berlin, Germany) · 2021Review
- Renal biomarkers of acute kidney injury in response to increasing intermittent hypoxia episodes in the neonatal rat.BMC nephrology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the outcome of extremely low birth weight (ELBW) infants with a history of acute kidney injury (AKI).
methodIn a retrospective, case control study, medical records of all ELBW infants admitted to the neonatal intensive care unit (NICU) between Jan 2002 and Dec 2011 were reviewed. Medical records were reviewed for infants' demographics, blood pressure (BP) at NICU discharge and at ≥3 years, and estimated glomerular filtration rate (eGFR) at ≥2 years.
resultsDuring the study period, 222 patients met the inclusion criteria, of whom 10% (23 out of 222) had AKI stage 2 and 3, 39% (87 out of 222) had AKI stage 1, and the rest did not have AKI. At NICU discharge, there was a difference in diastolic BP (DBP) among infants who had AKI stages 2 and 3, those who had stage 1, and those who did not have AKI (53 ± 12 vs 46 ± 9 vs 46 ± 11 mmHg respectively; p = 0.007), and 11% (23 out of 209) had hypertension (HTN). Although there was a significant correlation between the rise in SCr and DBP at NICU discharge in infants with AKI (R = 0.304; p = 0.004), there was no difference in HTN between infants with and those without AKI. At ≥2 years of age, 4% (5 out of 120) across all groups had an eGFR < 90 ml/min/1.73m
conclusionAt NICU discharge, infants with AKI stages 2 and 3 have a higher DBP than infants with stage 1 AKI and those who did not have AKI. However, there is no difference in the rate of HTN between the two groups. At ≥2 years ELBW infants are at risk for CKD independently of whether or not they develop neonatal AKI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.