Evidence map›Paper›PMID 28194557›Full record

ArticleLipids2017

(4Z,15Z)-Octadecadienoic Acid Inhibits Glycogen Synthase Kinase-3β and Glucose Production in H4IIE Cells.

Jun Yoshida, Shota Uesugi, Tetsuaki Kawamura, Ken-Ichi Kimura, Dawei Hu, Shuang Xia, Naoki Toyooka, Masao Ohnishi, Hideki Kawashima

Abstract read
PubMed Publisher
In one paragraph

Article in Lipids, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Jun YoshidaCenter for Liberal Arts and Sciences, Iwate Medical University, Yahaba, Iwate, 028-3694, Japan.
Shota UesugiThe United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate, 020-8550, Japan.
Tetsuaki KawamuraGraduate School of Agriculture, Iwate University, Morioka, Iwate, 020-8550, Japan.
Ken-Ichi KimuraThe United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate, 020-8550, Japan.
Dawei HuGraduate School of Innovative Life Science, University of Toyama, 3190 Gofuku, Toyama, 930-8555, Japan.
Shuang XiaGraduate School of Science and Engineering, University of Toyama, 3190 Gofuku, Toyama, 930-8555, Japan.
Naoki ToyookaGraduate School of Innovative Life Science, University of Toyama, 3190 Gofuku, Toyama, 930-8555, Japan.
Masao OhnishiDepartment of Food Science and Human Nutrition, Faculty of Human Life Sciences, Fuji Women's University, Ishikari, 061-3204, Japan.
Hideki KawashimaBioscience Laboratory, Miyako College, Iwate Prefectural University, Miyako, 027-0039, Japan. ajoe@iwate-pu.ac.jp.
Iwate University · JPUniversity of Toyama · JPFuji Women's University · JPIwate Medical University · JPWeatherford College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many uncommon non-methylene-interrupted fatty acids (NMI FA) are present in limpet gonads, but their biological properties remain unknown. To investigate new biological effects of naturally occurring NMI FA in eukaryotic cells, the biological activities of structurally analogous (4Z,15Z)-octadecadienoic acid (1), (9Z,20Z)-tricosadienoic acid (2), and (12Z,23Z)-hexacosadienoic acid (3) were examined by using a yeast-based drug-screening system using the Ca

Indexed as

AnimalsCalcineurinCalciumCell LineCell SurvivalDrug Evaluation, PreclinicalFatty Acids, UnsaturatedGlucoseGlycogen Synthase Kinase 3 betaHL-60 CellsHumansRatsSaccharomyces cerevisiaeCalcineurinCalciumFatty Acids, UnsaturatedGlucoseGlycogen Synthase Kinase 3 betaGsk3b protein, ratoctadecadienoic acid(12Z, 23Z)-Hexacosadienoic acid(4Z, 15Z)-Octadecadienoic acid(9Z, 20Z)-Tricosadienoic acidGSK-3βH4IIE cellsNon-methylene-interrupted fatty acid

Identifiers

PMID28194557
OpenAlexW2587347025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.