Evidence map›Paper›PMID 28194437›Full record

ArticleJCI insight2017

Mitochondrial quality-control dysregulation in conditional HO-1

Hagir B Suliman, Jeffrey E Keenan, Claude A Piantadosi

Open access · goldAbstract read
In one paragraph

Article in JCI insight, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

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  16. The Combination of ΔCancers · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hagir B SulimanDepartment of Medicine.
Jeffrey E KeenanDepartment of Surgery, and.
Claude A PiantadosiDepartment of Medicine.
Duke University · US

Funding

Mesenchymal Stromal Cell Conditioning by Carbon MonoxideP01HL108801 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHOI, AUGUSTINE M · 2011 to 2015
$13.8M
NHLBI NIH HHS P01 HL108801
6 · The paper itself

Abstract

The heme oxygenase-1 (

Indexed as

Oxidative StressAnimalsCardiomyopathiesCell DeathCells, CulturedGene Expression RegulationGene Knockout TechniquesHeme Oxygenase-1Membrane ProteinsMiceMitochondriaMitophagyMyocytes, CardiacNuclear Respiratory Factor 1Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaHeme Oxygenase-1Hmox1 protein, mouseMembrane ProteinsNrf1 protein, mouseNuclear Respiratory Factor 1Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, mouse

Identifiers

PMID28194437
PMCPMC5291731
OpenAlexW2586553264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.