Evidence map›Paper›PMID 28194314›Full record

ArticlePeerJ2017

Evolutionary and functional implications of hypervariable loci within the skin virome.

Geoffrey D Hannigan, Qi Zheng, Jacquelyn S Meisel, Samuel S Minot, Frederick D Bushman, Elizabeth A Grice

Abstract read
In one paragraph

Article in PeerJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Neonatal sepsis and the skin microbiome.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Review
  7. Review
  8. Microbiome of Barrier Organs in Allergy: Who Runs the World? Germs!Handbook of experimental pharmacology · 2022
    Review
  9. Review
  10. Defensive hypervariable regions confer superinfection exclusion in microviruses.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Bacteriophages of the lower urinary tract.Nature reviews. Urology · 2019
    Review
  16. [Atopic eczema and microbiome].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2019
    Review
  17. The Dynamics of the Skin's Immune System.International journal of molecular sciences · 2019
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Geoffrey D HanniganDepartment of Dermatology, University of Pennsylvania , Philadelphia, PA , USA.
Qi ZhengDepartment of Dermatology, University of Pennsylvania , Philadelphia, PA , USA.
Jacquelyn S MeiselDepartment of Dermatology, University of Pennsylvania , Philadelphia, PA , USA.
Samuel S MinotOne Codex , San Francisco, CA , USA.ORCID 0000-0003-1639-3905
Frederick D BushmanDepartment of Microbiology, University of Pennsylvania , Philadelphia, PA , USA.
Elizabeth A GriceDepartment of Dermatology, University of Pennsylvania, Philadelphia, PA, USA; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0003-3939-2200

Funding

Training Program in Computational GenomicsT32HG000046 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI JUNHYONG KIM, Mingyao Li · 1999 to 2026
$9.5M
Study Design and Data AnalysisP30AR069589 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI Elizabeth Anne Grice · 2016 to 2026
$8.6M
Skin microbiome interactions with complementR01AR066663 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI GRICE, ELIZABETH ANNE · 2015 to 2019
$1.8M
The Microbiome of Impaired Wound HealingR00AR060873 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI GRICE, ELIZABETH ANNE · 2012 to 2014
$730k
NHGRI NIH HHS T32 HG000046NIAMS NIH HHS P30 AR069589NIAMS NIH HHS R00 AR060873NIAMS NIH HHS R01 AR066663
6 · The paper itself

Abstract

Localized genomic variability is crucial for the ongoing conflicts between infectious microbes and their hosts. An understanding of evolutionary and adaptive patterns associated with genomic variability will help guide development of vaccines and antimicrobial agents. While most analyses of the human microbiome have focused on taxonomic classification and gene annotation, we investigated genomic variation of skin-associated viral communities. We evaluated patterns of viral genomic variation across 16 healthy human volunteers. Human papillomavirus (HPV) and

Indexed as

BacteriophageDermatologyEvolutionGenomic variabilityMetagenomicsVirome

Identifiers

PMID28194314
PMCPMC5299996

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.