Evidence map›Paper›PMID 28194155›Full record

ArticleFrontiers in plant science2017

Functional Characterization of CYP716 Family P450 Enzymes in Triterpenoid Biosynthesis in Tomato.

Shuhei Yasumoto, Hikaru Seki, Yuko Shimizu, Ery O Fukushima, Toshiya Muranaka

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Differential Analysis of Sesquiterpenoids ofMolecules (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Genome-wide identification and expression analysis ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Proteomic Changes in Response toPlants (Basel, Switzerland) · 2022
    Article
  10. Article
  11. First report of triterpenes pathway inSaudi journal of biological sciences · 2022
    Article
  12. Review
  13. Review
  14. Article
  15. α-Amyrin and β-Amyrin Isolated fromMolecules (Basel, Switzerland) · 2021
    Article
  16. Polyploidy underlies co-option and diversification of biosynthetic triterpene pathways in the apple tribe.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shuhei YasumotoDepartment of Biotechnology, Graduate School of Engineering, Osaka University Suita, Japan.
Hikaru SekiDepartment of Biotechnology, Graduate School of Engineering, Osaka University Suita, Japan.
Yuko ShimizuDepartment of Biotechnology, Graduate School of Engineering, Osaka University Suita, Japan.
Ery O FukushimaDepartment of Biotechnology, Graduate School of Engineering, Osaka UniversitySuita, Japan; Center for Open Innovation Research and Education, Graduate School of Engineering, Osaka UniversitySuita, Japan.
Toshiya MuranakaDepartment of Biotechnology, Graduate School of Engineering, Osaka University Suita, Japan.
Osaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triterpenoids are a group of structurally diverse specialized metabolites that frequently show useful bioactivities. These chemicals are biosynthesized from the common precursor 2,3-oxidosqualene in plants. The carbon skeletons produced by oxidosqualene cyclase (OSC) are usually modified by cytochrome P450 monooxygenases (P450s) and UDP-dependent glycosyltransferases. These biosynthetic enzymes contribute to the structural diversification of plant triterpenoids. Until now, many P450 enzymes have been characterized as triterpenoid oxidases. Among them, the CYP716 family P450 enzymes, which have been isolated from a wide range of plant families, seem to contribute to the triterpenoid structural diversification. Many CYP716 family P450 enzymes have been characterized as the multifunctional triterpene C-28 oxidases, which oxidize α-amyrin and β-amyrin to the widely distributed triterpenoids ursolic and oleanolic acids, respectively. Tomato (

Indexed as

C-28 oxidaseC-6β oxidaseCYP716 familyCytochrome P450 monooxygenasetomatotriterpenoid biosynthesis

Identifiers

PMID28194155
PMCPMC5278499
OpenAlexW2582213587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.