Evidence map›Paper›PMID 28194150›Full record

ArticleFrontiers in immunology2016

Epigenetic Regulation of Interleukin 6 by Histone Acetylation in Macrophages and Its Role in Paraquat-Induced Pulmonary Fibrosis.

Lingli Hu, Yanfang Yu, Huijie Huang, Hanting Fan, Li Hu, Caiyong Yin, Kai Li, David J R Fulton, Feng Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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  17. Tricarboxylic acid cycle metabolites: new players in macrophage.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Lingli HuDepartment of Forensic Medicine, Nanjing Medical University , Nanjing , China.
Yanfang YuDepartment of Forensic Medicine, Nanjing Medical University , Nanjing , China.
Huijie HuangDepartment of Forensic Medicine, Nanjing Medical University , Nanjing , China.
Hanting FanDepartment of Forensic Medicine, Nanjing Medical University , Nanjing , China.
Li HuDepartment of Forensic Medicine, Nanjing Medical University , Nanjing , China.
Caiyong YinDepartment of Forensic Medicine, Nanjing Medical University , Nanjing , China.
Kai LiDepartment of Forensic Medicine, Nanjing Medical University , Nanjing , China.
David J R FultonVascular Biology Center, Augusta University, Augusta, GA, USA; Department of Pharmacology, Augusta University, Augusta, GA, USA.
Feng ChenDepartment of Forensic Medicine, Nanjing Medical University, Nanjing, China; Vascular Biology Center, Augusta University, Augusta, GA, USA.
Nanjing Medical University · CNAugusta University Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overexpression of interleukin 6 (

Indexed as

epigeneticsforensic toxicologyhistone acetylationIL-6paraquatpulmonary fibrosis

Identifiers

PMID28194150
PMCPMC5276821
OpenAlexW2580243775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.