Evidence map›Paper›PMID 28193903›Full record

ArticleJournal of bacteriology2017

Structural Analysis of Mycobacterium tuberculosis Homologues of the Eukaryotic Proteasome Assembly Chaperone 2 (PAC2).

Lin Bai, Jordan B Jastrab, Marta Isasa, Kuan Hu, Hongjun Yu, Steven P Gygi, K Heran Darwin, Huilin Li

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. AAA+ Machines of Protein Destruction in Mycobacteria.Frontiers in molecular biosciences · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Lin BaiCryo-EM Structural Biology Laboratory, Van Andel Research Institute, Grand Rapids, Michigan, USA.
Jordan B JastrabDepartment of Microbiology, New York University School of Medicine, New York, New York, USA.
Marta IsasaDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
Kuan HuGraduate Program in Biochemistry and Structural Biology, Stony Brook University, Stony Brook, New York, USA.
Hongjun YuCryo-EM Structural Biology Laboratory, Van Andel Research Institute, Grand Rapids, Michigan, USA.
Steven P GygiDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
K Heran DarwinDepartment of Microbiology, New York University School of Medicine, New York, New York, USA heran.darwin@med.nyu.edu huilin.li@vai.org.
Huilin LiCryo-EM Structural Biology Laboratory, Van Andel Research Institute, Grand Rapids, Michigan, USA heran.darwin@med.nyu.edu huilin.li@vai.org.
Van Andel Institute · USHarvard University · USNew York University · USStony Brook University · US

Funding

Life Science and Biomedical technology Research center at NSLS-II LSBRP41GM111244 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI MCSWEENEY, SEAN · 2014 to 2018
$16.4M
New Sample Multiplexing Technologies to Identify Chemical Probes and Illuminate Ubiquitin BiologyR01GM067945 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GYGI, STEVEN P · 2003 to 2024
$10.5M
INFECTIOUS DISEASES &BASIC MICROBIOLOGICAL MECHANISMST32AI007180 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WEISER, JEFFREY NEAL · 1985 to 2022
$8.9M
PROTEASOME-DEPENDENT DEGRADATION IN MYCOBACTERIUM TUBERCULOSISR01AI088075 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Katerina Heran Darwin · 2011 to 2026
$6.5M
Structure Biology of Mycobacterium Tuberculosis Pup-Proteasome PathwayR01AI070285 · NIAID · VAN ANDEL RESEARCH INSTITUTE · PI LI, HUILIN · 2007 to 2022
$6.5M
Characterization of a novel cofactor of the M. tuberculosis proteasomeF30AI110067 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JASTRAB, JORDAN B · 2014 to 2017
$111k
NIAID NIH HHS F30 AI110067NIAID NIH HHS R01 AI070285NIAID NIH HHS R01 AI088075NIAID NIH HHS T32 AI007180NIGMS NIH HHS P41 GM111244NIGMS NIH HHS R01 GM067945
6 · The paper itself

Abstract

A previous bioinformatics analysis identified the

Indexed as

AnimalsArchaeaBacterial ProteinsCrystallography, X-RayModels, MolecularMolecular ChaperonesMycobacterium tuberculosisProteasome Endopeptidase ComplexProtein BindingProtein MultimerizationProteomicsSaccharomyces cerevisiae ProteinsBacterial ProteinsMolecular ChaperonesPba1 protein, S cerevisiaeProteasome Endopeptidase ComplexSaccharomyces cerevisiae ProteinsMycobacterium tuberculosisproteasomeprotein chaperonestructural biology

Identifiers

PMID28193903
PMCPMC5388811
OpenAlexW2588132220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.