Evidence map›Paper›PMID 28193827›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Monocyte Subsets Coregulate Inflammatory Responses by Integrated Signaling through TNF and IL-6 at the Endothelial Cell Interface.

Myriam Chimen, Clara M Yates, Helen M McGettrick, Lewis S C Ward, Matthew J Harrison, Bonita Apta, Lea H Dib, Beat A Imhof, Paul Harrison, Gerard B Nash and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 107 citations in OpenAlex.

  1. Trial
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  3. Article
  4. Review
  5. Article
  6. Induction of the ISR by AB5 subtilase cytotoxin drives type-I IFN expression in pDCs via STING activation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Review
  9. Observational
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Liver endothelial cells in NAFLD and transition to NASH and HCC.Cellular and molecular life sciences : CMLS · 2023
    Review
  18. Article
  19. Article
  20. Cerebrospinal fluid CD14Journal of neurovirology · 2023
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

Myriam ChimenInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.ORCID 0000-0002-3567-1731
Clara M YatesInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.ORCID 0000-0003-3218-7941
Helen M McGettrickInstitute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom; and.ORCID 0000-0002-5950-8840
Lewis S C WardInstitute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom; and.ORCID 0000-0002-5087-6305
Matthew J HarrisonInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Bonita AptaInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Lea H DibInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Beat A ImhofDepartment of Pathology and Immunology, University of Geneva, 1211 Geneva, Switzerland.
Paul HarrisonInstitute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom; and.ORCID 0000-0003-4610-8909
Gerard B NashInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.ORCID 0000-0002-5935-2831
G Ed RaingerInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom; g.e.rainger@bham.ac.uk.
University of Birmingham · GBUniversity of Geneva · CH

Funding

Arthritis Research UK 19899Biotechnology and Biological Sciences Research Council BBS/B/01057British Heart Foundation FS/14/42/30956British Heart Foundation PG/09/069/27905British Heart Foundation PG/11/49/28983British Heart Foundation RG/12/7/29693Versus Arthritis 19899
6 · The paper itself

Abstract

Two major monocyte subsets, CD14

Indexed as

Cell SeparationChemotaxis, LeukocyteEndothelial CellsFlow CytometryHumansInflammationInterleukin-6MonocytesPolymerase Chain ReactionSignal TransductionTumor Necrosis Factor-alphaIL6 protein, humanInterleukin-6Tumor Necrosis Factor-alpha

Identifiers

PMID28193827
PMCPMC5357784
OpenAlexW2793932682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.