Evidence map›Paper›PMID 28193826›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

The NLRP3 Inflammasome Has a Critical Role in Peritoneal Dialysis-Related Peritonitis.

Nicolas Hautem, Johann Morelle, Amadou Sow, Cyril Corbet, Olivier Feron, Eric Goffin, François Huaux, Olivier Devuyst

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  5. NLRP3 inflammasome inhibition decreasesInfection and immunity · 2024
    Article
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  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. GATA6Frontiers in pharmacology · 2022
    Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Nicolas HautemInstitut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium.
Johann MorelleInstitut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium.
Amadou SowInstitut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium.
Cyril CorbetInstitut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium.
Olivier FeronInstitut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium.
Eric GoffinDivision of Nephrology, Cliniques universitaires Saint-Luc, Brussels, Belgium; and.
François HuauxInstitut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium.
Olivier DevuystInstitut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium; olivier.devuyst@uzh.ch.
UCLouvain · BECliniques Universitaires Saint-Luc · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial peritonitis remains the main cause of technique failure in peritoneal dialysis (PD). During peritonitis, the peritoneal membrane undergoes structural and functional alterations that are mediated by IL-1

Indexed as

Peritoneal DialysisAgedAged, 80 and overAnimalsFemaleHumansInflammasomesInterleukin-1betaMaleMiceMiddle AgedNLR Family, Pyrin Domain-Containing 3 ProteinPeritonitisInflammasomesInterleukin-1betaNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanNlrp3 protein, mouseanakinracytokinesInterleukin-1peritoneal membraneultrafiltrationvascular permeability

Identifiers

PMID28193826
PMCPMC5491280
OpenAlexW2588024686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.