Evidence map›Paper›PMID 28193782›Full record

ArticlePhysiological reports2017

Mitochondrial mass and activity as a function of body composition in individuals with spinal cord injury.

Laura C O'Brien, Rodney C Wade, Liron Segal, Qun Chen, Jeannie Savas, Edward J Lesnefsky, Ashraf S Gorgey

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01652040 (Effects of Evoked Resistance Training and Testosterone After Spinal Cord Injury), which is not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01652040 phase2 / phase3completednot on this map

Effects of Evoked Resistance Training and Testosterone After Spinal Cord Injury

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2012 to 2017Enrolled26ConditionsSpinal Cord InjuryArmsResistance Training and Testosterone Patches, Testosterone Patches
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Laura C O'BrienSpinal Cord Injury and Disorders, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia.
Rodney C WadeSpinal Cord Injury and Disorders, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia.
Liron SegalSpinal Cord Injury and Disorders, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia.
Qun ChenDepartment of Medicine, Division of Cardiology, Pauley Heart Center Virginia Commonwealth University, Richmond, Virginia.
Jeannie SavasDepartment of Surgery, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia.
Edward J LesnefskyDepartment of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia.
Ashraf S GorgeySpinal Cord Injury and Disorders, Hunter Holmes McGuire VA Medical Center, Richmond, Virginia ashraf.gorgey@va.gov.
Virginia Commonwealth University · USHunter Holmes McGuire VA Medical Center · US

Funding

BLRD VA I01 BX001355
6 · The paper itself

Abstract

Spinal cord injury (SCI) is accompanied by deterioration in body composition and severe muscle atrophy. These changes put individuals at risk for insulin resistance, type II diabetes, and cardiovascular disease. To determine the relationships between skeletal muscle mitochondrial mass, activity, and body composition, 22 men with motor complete SCI were studied. Body composition assessment was performed using dual-energy X-ray absorptiometry and magnetic resonance imaging. Skeletal muscle biopsies were obtained from the vastus lateralis muscle to measure citrate synthase (CS) and complex III (CIII) activity. CS activity was inversely related to %body fat (

Indexed as

Body CompositionAbsorptiometry, PhotonAdipose TissueAdolescentAdultCitrate (si)-SynthaseElectron Transport Complex IIIHumansMagnetic Resonance ImagingMaleMiddle AgedMitochondriaMuscle, SkeletalSpinal Cord InjuriesYoung AdultCitrate (si)-SynthaseElectron Transport Complex IIIBody compositionmetabolismMitochondriaskeletal musclespinal cord injuries

Identifiers

PMID28193782
PMCPMC5309572
OpenAlexW2588416809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.