Evidence map›Paper›PMID 28193730›Full record

ArticleGenetics2017

Mismatch Repair Incompatibilities in Diverse Yeast Populations.

Duyen T Bui, Anne Friedrich, Najla Al-Sweel, Gianni Liti, Joseph Schacherer, Charles F Aquadro, Eric Alani

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Duyen T BuiDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853-2703.
Anne FriedrichUniversité de Strasbourg, Centre National de la Recherche Scientifique, Génétique Moléculaire, Génomique, Microbiologie, Unité Mixte de Recherche, 7156, F-67000 Strasbourg, France.
Najla Al-SweelDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853-2703.
Gianni LitiInstitute for Research on Cancer and Ageing of Nice, 06107 Nice, France.
Joseph SchachererUniversité de Strasbourg, Centre National de la Recherche Scientifique, Génétique Moléculaire, Génomique, Microbiologie, Unité Mixte de Recherche, 7156, F-67000 Strasbourg, France.
Charles F AquadroDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853-2703.
Eric AlaniDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853-2703 eea3@cornell.edu.ORCID 0000-0002-5011-9339
Cornell University · USGénétique Moléculaire Génomique Microbiologie · FRInstitut de Recherche sur le Cancer et le Vieillissement de Nice · FRUniversité de Strasbourg · FR

Funding

Roles for Mismatch Repair Proteins in Maintaining Genome StabilityR01GM053085 · NIGMS · CORNELL UNIVERSITY ITHACA · PI ALANI, ERIC E. · 1995 to 2019
$7.3M
Adaptive Protein Evolution of the Drosophila Germline Stem Cell Gene Bag of MarblesR01GM095793 · NIGMS · CORNELL UNIVERSITY · PI AQUADRO, CHARLES F · 2011 to 2024
$3.9M
NIGMS NIH HHS R01 GM053085NIGMS NIH HHS R01 GM095793
6 · The paper itself

Abstract

An elevated mutation rate can provide cells with a source of mutations to adapt to changing environments. We identified a negative epistatic interaction involving naturally occurring variants in the

Indexed as

DNA Mismatch RepairEvolution, MolecularGenetic BackgroundGenetic FitnessHomozygoteMutation RateMutL Protein Homolog 1MutL ProteinsPhenotypeSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsMLH1 protein, S cerevisiaeMutL Protein Homolog 1MutL ProteinsPMS1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsadaptationDNA mismatch repairexperimental evolutiongenetic incompatibilitymutator phenotypenatural yeast isolatesSaccharomyces cerevisiae

Identifiers

PMID28193730
PMCPMC5378106
OpenAlexW2589081037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.