Evidence map›Paper›PMID 28193704›Full record

Trial reportJournal of investigative medicine : the official publication of the American Federation for Clinical Research2017

Emma L Davey, Rhonda E Colombo, Charles Fiorentino, Gary Fahle, Richard T Davey, Kenneth N Olivier, Joseph A Kovacs

Registry-linked trialOpen access · greenAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01113034 (A Phase 1 Randomized Double-Blind Placebo-Crossover Safety Trial of DAS181), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01113034 phase1completednot on this map

A Phase 1 Randomized Double-Blind Placebo-Crossover Safety Trial of DAS181 (Fludase®) in Adult Subjects With Well-Controlled Asthma or Bronchiectasis

TypeinterventionalSponsorAnsun Biopharma, Inc.Ran2010 to 2011Enrolled11ConditionsAsthma, BronchiectasisArmsDAS181 dry powder, formulation F02, Respitose ML006 (DMV-Fonterra)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Strain-Dependent Protective Innate Immunity AgainstJournal of fungi (Basel, Switzerland) · 2026
    Article
  4. Protective innate immunity againstInfection and immunity · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Emma L DaveyCritical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, Maryland, USA.
Rhonda E ColomboDivision of Infectious Diseases, Augusta University, Augusta, Georgia, USA.
Charles FiorentinoDivision of Clinical Research, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Gary FahleDepartment of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, Maryland, USA.
Richard T DaveyLaboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Kenneth N OlivierLaboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Joseph A KovacsCritical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, Maryland, USA.
National Institutes of Health Clinical Center · USNational Institute of Allergy and Infectious Diseases · USAugusta University · USNational Heart Lung and Blood Institute · US

Funding

Immunologic And Virologic Approaches To HIV-1 TherapeuticsZIAAI000865 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DAVEY, RICHARD · 2009 to 2019
$8.8M
Inflammatory and immune dysregulation associated lung diseaseZIAHL006201 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI OLIVIER, KENNETH · 2015 to 2022
$2.1M
Molecular Studies Of Human Pneumocystis CariniiZIACL000192 · CLC · CLINICAL CENTER · PI KOVACS, JOSEPH A · 2009 to 2025
$0k
Intramural NIH HHS ZIA CL000192
6 · The paper itself

Abstract

TRIAL REGISTRATION NUMBER: NCT01113034.

Indexed as

Administration, OralAdrenal Cortex HormonesAdultAsthmaColony Count, MicrobialFemaleHumansMaleMiddle AgedPneumocystisSputumYoung AdultAdrenal Cortex HormonesAsthmaLung Diseases

Identifiers

PMID28193704
PMCPMC6309956
OpenAlexW2588257346

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.