Evidence map›Paper›PMID 28193664›Full record

ArticleAntimicrobial agents and chemotherapy2017

Teresa I Ng, Preethi Krishnan, Tami Pilot-Matias, Warren Kati, Gretja Schnell, Jill Beyer, Thomas Reisch, Liangjun Lu, Tatyana Dekhtyar, Michelle Irvin and 5 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. Efficacy and Safety of Glecaprevir/Pibrentasvir in Patients Coinfected With Hepatitis C Virus and Human Immunodeficiency Virus Type 1: The EXPEDITION-2 Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Teresa I NgAbbVie, Inc., North Chicago, Illinois, USA teresa.ng@abbvie.com.
Preethi KrishnanAbbVie, Inc., North Chicago, Illinois, USA.
Tami Pilot-MatiasAbbVie, Inc., North Chicago, Illinois, USA.
Warren KatiAbbVie, Inc., North Chicago, Illinois, USA.
Gretja SchnellAbbVie, Inc., North Chicago, Illinois, USA.
Jill BeyerAbbVie, Inc., North Chicago, Illinois, USA.
Thomas ReischAbbVie, Inc., North Chicago, Illinois, USA.
Liangjun LuAbbVie, Inc., North Chicago, Illinois, USA.
Tatyana DekhtyarAbbVie, Inc., North Chicago, Illinois, USA.
Michelle IrvinAbbVie, Inc., North Chicago, Illinois, USA.
Rakesh TripathiAbbVie, Inc., North Chicago, Illinois, USA.
Clarence MaringAbbVie, Inc., North Chicago, Illinois, USA.
John T RandolphAbbVie, Inc., North Chicago, Illinois, USA.
Rolf WagnerAbbVie, Inc., North Chicago, Illinois, USA.
Christine CollinsAbbVie, Inc., North Chicago, Illinois, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pibrentasvir (ABT-530) is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with 50% effective concentration (EC

Indexed as

Amino Acid SubstitutionAntiviral AgentsBenzimidazolesCell Line, TumorDrug Resistance, ViralHepacivirusHepatitis CHep G2 CellsHumansPyrrolidinesRNA-Dependent RNA PolymeraseViral Nonstructural ProteinsAntiviral AgentsBenzimidazolesNS-5 protein, hepatitis C viruspibrentasvirPyrrolidinesRNA-Dependent RNA PolymeraseViral Nonstructural ProteinsABT-530antiviral activityHCVNS5A inhibitorpibrentasvirresistance

Identifiers

PMID28193664
PMCPMC5404558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.