Evidence map›Paper›PMID 28193210›Full record

SynthesisBMC surgery2017

Hepatectomy for liver metastases from gastric cancer: a systematic review.

Ying-Yang Liao, Ning-Fu Peng, Di Long, Peng-Cheng Yu, Sen Zhang, Jian-Hong Zhong, Le-Qun Li

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. BRAZILIAN GASTRIC CANCER ASSOCIATION GUIDELINES (PART 2): UPDATE ON TREATMENT.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Surgical management of metastatic gastric cancer: moving beyond the guidelines.Translational gastroenterology and hepatology · 2019
    Review
  20. [Oligometastases in gastric and esophageal cancer : Current clinical trials and surgical concepts].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying-Yang LiaoNutrition Department, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China.
Ning-Fu PengHepatobiliary Surgery Department, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Province, China.
Di LongColorectal Anal Surgery Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Peng-Cheng YuColorectal Anal Surgery Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Sen ZhangColorectal Anal Surgery Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Jian-Hong ZhongHepatobiliary Surgery Department, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Province, China. zhongjianhong66@163.com.ORCID http://orcid.org/0000-0002-1494-6396
Le-Qun LiHepatobiliary Surgery Department, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOfficial guidelines recommend palliative treatments for patients with liver metastases from gastric cancer. However, many case series reported that hepatectomy for such cases is safe and effective. This systematic review compares the overall survival between hepatectomy and palliative therapy in patients with liver metastases from gastric cancer.

methodsTwo independent reviewers performed a systematic search of literature in EMBASE and PubMed, updated until 26 October 2016. The Newcastle-Ottawa score for cohort studies was used for quality assessment of included studies.

resultsA total of eight cohort studies involving 196 patients in the hepatectomy arm and 481 in the palliative arm were included. Median overall survival of patients in the two arms was 23.7 (range, 13.0 to 48.0) and 7.6 (range, 5.5 to 15.2), respectively. Median rates of overall survival of the two arms were 69, 40, 33 and 27, 8, 4% at 1, 2, and 3 years, respectively. Comparing with palliative therapy, hepatectomy was associated with significantly lower mortality at 1 year (odds ratio 0.17, P < 0.001) and 2 years (odds ratio 0.15, P < 0.001). Among the patients who underwent hepatectomy, Asian cohorts showed higher median rates of overall survival than Western cohorts at 1 year (76 vs. 60%), 2 years (47 vs. 30%) and 3 years (39 vs. 23%).

conclusionsHepatectomy in the management of liver metastases from gastric cancer can be considered effective. In the elective setting, hepatectomy provides a potential alternative to palliative therapy.

Indexed as

HepatectomyHumansLiver NeoplasmsStomach NeoplasmsGastric cancerHepatectomyLiver metastasesSystematic review

Identifiers

PMID28193210
PMCPMC5307809

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.