Evidence map›Paper›PMID 28193193›Full record

ArticleBMC pulmonary medicine2017

Observation management of pulmonary embolism and agreement with claims-based and clinical risk stratification criteria in United States patients: a retrospective analysis.

Elaine Nguyen, Craig I Coleman, W Frank Peacock, Philip S Wells, Erin R Weeda, Veronica Ashton, Concetta Crivera, Peter Wildgoose, Jeff R Schein, Thomas J Bunz and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Elaine NguyenUniversity of Connecticut School of Pharmacy, 69 North Eagleville Road, Unit 3092, Storrs, CT, 06269, USA.
Craig I ColemanUniversity of Connecticut School of Pharmacy, 69 North Eagleville Road, Unit 3092, Storrs, CT, 06269, USA. craig.coleman@hhchealth.org.
W Frank PeacockDepartment of Emergency Medicine, Baylor College of Medicine, 1504 Taub Loop, Houston, TX, USA.
Philip S WellsDepartment of Medicine, University of Ottawa, Ottawa Hospital Research Institute, 501 Smyth Road, Box 206, Ottawa, ON, Canada.
Erin R WeedaUniversity of Connecticut School of Pharmacy, 69 North Eagleville Road, Unit 3092, Storrs, CT, 06269, USA.
Veronica AshtonJanssen Scientific Affairs, LLC, 1000 Route 202, Raritan, NJ, USA.
Concetta CriveraJanssen Scientific Affairs, LLC, 1000 Route 202, Raritan, NJ, USA.
Peter WildgooseJanssen Scientific Affairs, LLC, 1000 Route 202, Raritan, NJ, USA.
Jeff R ScheinJanssen Scientific Affairs, LLC, 1000 Route 202, Raritan, NJ, USA.
Thomas J BunzNew England Health Analytics, LLC, Granby, CT, USA.
Gregory J FermannDepartment of Emergency Medicine, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH, USA.
University of Connecticut · USJanssen Scientific Affairs (United States)Janssen (United States) · USBaylor College of Medicine · USOttawa Hospital · CAUniversity of Cincinnati · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGuidelines suggest observation stays are appropriate for pulmonary embolism (PE) patients at low-risk for early mortality. We sought to assess agreement between United States (US) observation management of PE and claims-based and clinical risk stratification criteria.

methodsUsing US Premier data from 11/2012 to 3/2015, we identified adult observation stay patients with a primary diagnosis of PE, ≥1 PE diagnostic test claim and evidence of PE treatment. The proportion of patients at high-risk was assessed using the In-hospital Mortality for PulmonAry embolism using Claims daTa (IMPACT) equation and high-risk characteristics (age > 80 years, heart failure, chronic lung disease, renal or liver disease, high-risk for bleeding, cancer or need for thrombolysis/embolectomy).

resultsWe identified 1633 PE patients managed through an observation stay. Despite their observation status, IMPACT classified 46.4% as high-risk for early mortality and 33.3% had ≥1 high-risk characteristic. Co-morbid heart failure, renal or liver disease, high-risk for major bleeding, cancer and hemodynamic instability were low (each <4.5%), but 7.8% were >80 years-of-age and 19.4% had chronic lung disease.

conclusionMany PE patients selected for management in observation stay units appeared to have clinical characteristics suggestive of higher-risk for mortality based upon published claims-based and clinical risk stratification criteria.

Indexed as

AdultAgedAged, 80 and overComorbidityFemaleHospital MortalityHumansMaleMiddle AgedObservationPractice Guidelines as TopicPulmonary EmbolismRetrospective StudiesRisk AssessmentUnited StatesMortalityObservation staysPulmonary embolismResource utilization

Identifiers

PMID28193193
PMCPMC5307802
OpenAlexW2588735254

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.