Evidence map›Paper›PMID 28193176›Full record

Trial reportBMC cardiovascular disorders2017

Telemonitoring and/or self-monitoring of blood pressure in hypertension (TASMINH4): protocol for a randomised controlled trial.

Marloes Franssen, Andrew Farmer, Sabrina Grant, Sheila Greenfield, Carl Heneghan, Richard Hobbs, James Hodgkinson, Susan Jowett, Jonathan Mant, Una Martin and 7 more

Open access · goldAbstract readPragmatic Clinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Using mHealth for the management of hypertension in UK primary care: an embedded qualitative study of the TASMINH4 randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Marloes FranssenNuffield Department of Primary Care, Oxford University, Oxford, UK.
Andrew FarmerNuffield Department of Primary Care, Oxford University, Oxford, UK.
Sabrina GrantPrimary Care Clinical Sciences, University of Birmingham, Birmingham, UK.
Sheila GreenfieldPrimary Care Clinical Sciences, University of Birmingham, Birmingham, UK.
Carl HeneghanNuffield Department of Primary Care, Oxford University, Oxford, UK.
Richard HobbsNuffield Department of Primary Care, Oxford University, Oxford, UK.
James HodgkinsonPrimary Care Clinical Sciences, University of Birmingham, Birmingham, UK.
Susan JowettPrimary Care Clinical Sciences, University of Birmingham, Birmingham, UK.
Jonathan MantDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Una MartinPrimary Care Clinical Sciences, University of Birmingham, Birmingham, UK.
Siobhan MilnerPrimary Care Clinical Sciences, University of Birmingham, Birmingham, UK.
Mark MonahanPrimary Care Clinical Sciences, University of Birmingham, Birmingham, UK.
Emma OgburnNuffield Department of Primary Care, Oxford University, Oxford, UK.
Rafael Perera-SalazarNuffield Department of Primary Care, Oxford University, Oxford, UK.
Claire SchwartzNuffield Department of Primary Care, Oxford University, Oxford, UK.
Ly-Mee YuNuffield Department of Primary Care, Oxford University, Oxford, UK.
Richard J McManusNuffield Department of Primary Care, Oxford University, Oxford, UK. richard.mcmanus@phc.ox.ac.uk.
University of Oxford · GBUniversity of Birmingham · GBUniversity of Cambridge · GB

Funding

Department of Health IS-SPC-0514-10043Department of Health NIHR-RP-02-12-015
6 · The paper itself

Abstract

backgroundSelf-monitoring of hypertension is associated with lower systolic blood pressure (SBP). However, evidence for the use of self-monitoring to titrate antihypertensive medication by physicians is equivocal. Furthermore, there is some evidence for the efficacy of telemonitoring in the management of hypertension but it is not clear what this adds over and above self-monitoring. This trial aims to evaluate whether GP led antihypertensive titration using self-monitoring results in lower SBP compared to usual care and whether telemonitoring adds anything to self-monitoring alone. METHODS/

designThis will be a pragmatic primary care based, unblinded, randomised controlled trial of self-monitoring of BP with or without telemonitoring compared to usual care. Eligible patients will have poorly controlled hypertension (>140/90 mmHg) and will be recruited from primary care. Participants will be individually randomised to either usual care, self-monitoring alone, or self-monitoring with telemonitoring. The primary outcome of the trial will be difference in clinic SBP between intervention and control groups at 12 months adjusted for baseline SBP, gender, BP target and practice. At least 1110 patients will be sufficient to detect a difference in SBP between self-monitoring with or without telemonitoring and usual care of 5 mmHg with 90% power with an adjusted alpha of 0.017 (2-sided) to adjust for all three pairwise comparisons. Other outcomes will include adherence of anti-hypertensive medication, lifestyle behaviours, health-related quality of life, and adverse events. An economic analysis will consider both within trial costs and a model extrapolating the results thereafter. A qualitative sub study will gain insights into the views, experiences and decision making processes of patients and health care professionals focusing on the acceptability of self-monitoring and telemonitoring in the routine management of hypertension. DISCUSSION: The results of the trial will be directly applicable to primary care in the UK. If successful, self-monitoring of BP in people with hypertension would be applicable to hundreds of thousands of individuals in the UK.

trial registrationISRCTN 83571366 . Registered 17 July 2014.

Indexed as

Blood PressureBlood Pressure Monitoring, AmbulatoryTelemetryAntihypertensive AgentsBlood Pressure DeterminationClinical ProtocolsHumansHypertensionPredictive Value of TestsPrimary Health CareResearch DesignTelemedicineTreatment OutcomeUnited KingdomAntihypertensive AgentsHypertensionPrimary careSelf-monitoringTelemonitoring

Identifiers

PMID28193176
PMCPMC5307789
OpenAlexW2588617294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.