Evidence map›Paper›PMID 28192787›Full record

ArticleNature2017

m

Boxuan Simen Zhao, Xiao Wang, Alana V Beadell, Zhike Lu, Hailing Shi, Adam Kuuspalu, Robert K Ho, Chuan He

Open access · greenAbstract read
In one paragraph

Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 343 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
343citing papers in PubMed, 1 pooled it
25.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

343 citing papers in PubMed, 1 synthesis or guideline pooled it, 593 citations in OpenAlex.

  1. Pooled it
  2. NAR cancer · 2026
    Article
  3. Article
  4. RNA mJournal of advanced research · 2026
    Article
  5. Article
  6. Single-nucleotide RNA mCell reports · 2026
    Article
  7. Emerging roles of mJournal of assisted reproduction and genetics · 2026
    Review
  8. Single-molecule mbioRxiv : the preprint server for biology · 2026
    Article
  9. Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
    Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. FTO-mediated mActa pharmaceutica Sinica. B · 2026
    Article
  16. Article
  17. RNA modification systems as therapeutic targets.Nature reviews. Drug discovery · 2026
    Review
  18. Review
  19. Article
  20. Article

283 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Boxuan Simen ZhaoDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.
Xiao WangDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.
Alana V BeadellDepartment of Organismal Biology and Anatomy, The University of Chicago, 1027 East 57th Street, Chicago, Illinois 60637, USA.
Zhike LuDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.
Hailing ShiDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.
Adam KuuspaluDepartment of Organismal Biology and Anatomy, The University of Chicago, 1027 East 57th Street, Chicago, Illinois 60637, USA.
Robert K HoDepartment of Organismal Biology and Anatomy, The University of Chicago, 1027 East 57th Street, Chicago, Illinois 60637, USA.
Chuan HeDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.
Howard Hughes Medical Institute · USUniversity of Chicago · US

Funding

Recognition and mechanism of N6-methyl adenosine modificationsR01GM113194 · NIGMS · UNIVERSITY OF CHICAGO · PI PAN, TAO · 2015 to 2022
$2.5M
An Animal Model for Human Heart-Hand SyndromesR01HD072598 · NICHD · UNIVERSITY OF CHICAGO · PI HO, ROBERT K · 2013 to 2017
$1.6M
Base-resolution sequencing of m6A in RNAR01HG008688 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2015 to 2017
$1.3M
Howard Hughes Medical InstituteNHGRI NIH HHS R01 HG008688NICHD NIH HHS R01 HD072598NIGMS NIH HHS R01 GM113194
6 · The paper itself

Abstract

The maternal-to-zygotic transition (MZT) is one of the most profound and tightly orchestrated processes during the early life of embryos, yet factors that shape the temporal pattern of vertebrate MZT are largely unknown. Here we show that over one-third of zebrafish maternal messenger RNAs (mRNAs) can be N

Indexed as

RNA StabilityAdenosineAnimalsEmbryonic DevelopmentFemaleMaleRNA-Binding ProteinsRNA, Messenger, StoredTime FactorsZebrafishZebrafish ProteinsZygoteAdenosineN-methyladenosineRNA-Binding ProteinsRNA, Messenger, StoredYthdf2 protein, zebrafishZebrafish Proteins

Identifiers

PMID28192787
PMCPMC5323276
OpenAlexW2586247640

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.