Evidence map›Paper›PMID 28192494›Full record

ArticlePloS one2017

Edible solid lipid nanoparticles (SLN) as carrier system for antioxidants of different lipophilicity.

Kathleen Oehlke, Diana Behsnilian, Esther Mayer-Miebach, Peter G Weidler, Ralf Greiner

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
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  6. Article
  7. Article
  8. Article
  9. Features, applications, and sustainability of lipid nanoparticles in cosmeceuticals.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Review
  10. Review
  11. Review
  12. Article
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  14. Nanoscale Drug Delivery Systems: From Medicine to Agriculture.Frontiers in bioengineering and biotechnology · 2020
    Review
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kathleen OehlkeInstitute for Food Technology and Bioprocess Engineering, Max Rubner-Institut, Karlsruhe, Germany.
Diana BehsnilianInstitute for Food Technology and Bioprocess Engineering, Max Rubner-Institut, Karlsruhe, Germany.
Esther Mayer-MiebachInstitute for Food Technology and Bioprocess Engineering, Max Rubner-Institut, Karlsruhe, Germany.
Peter G WeidlerKarlsruhe Institute of Technology (KIT), Institute of Functional Interfaces, Division of oxidic and organic interfaces Hermann-von-Helmoltz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.
Ralf GreinerInstitute for Food Technology and Bioprocess Engineering, Max Rubner-Institut, Karlsruhe, Germany.
Max Rubner Institut · DEKarlsruhe Institute of Technology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferulic acid (FA) and tocopherol (Toc) loaded solid lipid nanoparticles (SLN) were prepared by a hot homogenisation method. The particle size distribution, zeta potential and melting behaviour of the SLN as well as the stability, encapsulation efficiency and radical scavenging activity of FA and Toc in the SLN were analysed. The different formulations containing up to 2.8 mg g-1 of FA or Toc were stable during at least 15 weeks of storage at room temperature. Despite partial degradation and / or release of FA and Toc during storage, significant radical scavenging activity was maintained. DSC measurements and radical scavenging tests after different time periods revealed that the re-structuring of the lipid matrix was connected to the enhanced antioxidant activity of Toc but did not affect the activity of FA.

Indexed as

AntioxidantsCalorimetry, Differential ScanningCoumaric AcidsDrug CarriersDrug CompoundingDrug Delivery SystemsDrug LiberationDrug StabilityDrug StorageFree Radical ScavengersHumansLipidsMicroscopy, Electron, ScanningNanoparticlesParticle SizeTemperatureAntioxidantsCoumaric AcidsDrug Carriersferulic acidFree Radical ScavengersLipidsTocopherols

Identifiers

PMID28192494
PMCPMC5305235
OpenAlexW2588383524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.