ArticlePLoS computational biology2017
Co-emergence of multi-scale cortical activities of irregular firing, oscillations and avalanches achieves cost-efficient information capacity.
Article in PLoS computational biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Critical neuronal avalanches arise from excitation-inhibition balanced spontaneous activity.iScience · 2026Article
- Theta-nested gamma oscillations balance prediction and vigilance in spatial navigation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Neural circuit mechanisms underlying dominance traits and social competition.Biophysics reviews · 2025Article
- Neural mechanisms balancing accuracy and flexibility in working memory and decision tasks.NPJ systems biology and applications · 2025Article
- Article
- Neuropeptide-Dependent Spike Time Precision and Plasticity in Circadian Output Neurons.The European journal of neuroscience · 2025Article
- Rectified activity-dependent population plasticity implicates cortical adaptation for memory and cognitive functions.Communications biology · 2024Article
- Article
- Multilevel and multifaceted brain response features in spiking, ERP and ERD: experimental observation and simultaneous generation in a neuronal network model with excitation-inhibition balance.Cognitive neurodynamics · 2023Article
- Comparative analysis of multifaceted neural effects associated with varying endogenous cognitive load.Communications biology · 2023Article
- Article
- Less is more: wiring-economical modular networks support self-sustained firing-economical neural avalanches for efficient processing.National science review · 2022Article
- Criticality enhances the multilevel reliability of stimulus responses in cortical neural networks.PLoS computational biology · 2022Article
- Gamma Oscillations Facilitate Effective Learning in Excitatory-Inhibitory Balanced Neural Circuits.Neural plasticity · 2021Article
- Differential effects of propofol and ketamine on critical brain dynamics.PLoS computational biology · 2020Article
- Hopf Bifurcation in Mean Field Explains Critical Avalanches in Excitation-Inhibition Balanced Neuronal Networks: A Mechanism for Multiscale Variability.Frontiers in systems neuroscience · 2020Article
- Compressive Sensing Inference of Neuronal Network Connectivity in Balanced Neuronal Dynamics.Frontiers in neuroscience · 2019Article
- Metabolic Cost of Dendritic CaFrontiers in neuroscience · 2019Article
- Efficient Coding and Energy Efficiency Are Promoted by Balanced Excitatory and Inhibitory Synaptic Currents in Neuronal Network.Frontiers in cellular neuroscience · 2018Article
- Features of spatial and functional segregation and integration of the primate connectome revealed by trade-off between wiring cost and efficiency.PLoS computational biology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The brain is highly energy consuming, therefore is under strong selective pressure to achieve cost-efficiency in both cortical connectivities and activities. However, cost-efficiency as a design principle for cortical activities has been rarely studied. Especially it is not clear how cost-efficiency is related to ubiquitously observed multi-scale properties: irregular firing, oscillations and neuronal avalanches. Here we demonstrate that these prominent properties can be simultaneously observed in a generic, biologically plausible neural circuit model that captures excitation-inhibition balance and realistic dynamics of synaptic conductance. Their co-emergence achieves minimal energy cost as well as maximal energy efficiency on information capacity, when neuronal firing are coordinated and shaped by moderate synchrony to reduce otherwise redundant spikes, and the dynamical clusterings are maintained in the form of neuronal avalanches. Such cost-efficient neural dynamics can be employed as a foundation for further efficient information processing under energy constraint.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.