Evidence map›Paper›PMID 28192151›Full record

ArticlePeptides2017

Angiotensin-(1-7)-dependent vasorelaxation of the renal artery exhibits unique angiotensin and bradykinin receptor selectivity.

Mariam H M Yousif, Ibrahim F Benter, Debra I Diz, Mark C Chappell

Abstract read
In one paragraph

Article in Peptides, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mariam H M YousifDepartment of Pharmacology & Toxicology, Faculty of Medicine, Kuwait University, Kuwait.
Ibrahim F BenterDepartment of Pharmacology & Toxicology, Faculty of Medicine, Kuwait University, Kuwait.
Debra I DizThe Hypertension & Vascular Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Mark C ChappellThe Hypertension & Vascular Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA. Electronic address: mchappel@wakehealth.edu.
Kuwait University · KWWake Forest University · US

Funding

Vaso-Hormonal Mechanisms in HypertensionP01HL051952 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI GROBAN, LEANNE · 1994 to 2019
$34.8M
Estrogen, ACE2 and Salt-SensitivityR01HL056973 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHAPPELL, MARK C · 2004 to 2008
$1.6M
Novel Angiotensin-(1-7) Endopeptidase in Fetal ProgrammingR21HD084227 · NICHD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHAPPELL, MARK C, ROSE, JAMES C. · 2016 to 2017
$426k
REGULATION AND FUNCTION OF ANGIOTENSIN (1-7)R29HL056973 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHAPPELL, MARK C · 1996 to 1999
–
NHLBI NIH HHS P01 HL051952NHLBI NIH HHS R01 HL056973NHLBI NIH HHS R29 HL056973NICHD NIH HHS R21 HD084227
6 · The paper itself

Abstract

Angiotensin-(1-7) [Ang-(1-7)] exhibits blood pressure lowering actions, inhibits cell growth, and reduces tissue inflammation and fibrosis which may functionally antagonize an activated Ang II-AT

Indexed as

Angiotensin IAngiotensin Receptor AntagonistsAnimalsBlood PressureBradykinin Receptor AntagonistsGuanylate CyclaseHumansImidazolesLosartanNG-Nitroarginine Methyl EsterNitric OxidePeptide FragmentsPhenylephrineProto-Oncogene MasPyridinesRatsAngiotensin Iangiotensin I (1-7)Angiotensin Receptor AntagonistsBradykinin Receptor AntagonistsD-Pro7-Ang-(1-7)Guanylate CyclaseImidazolesLosartanMAS1 protein, humanNG-Nitroarginine Methyl EsterNitric OxidePD 123319Peptide FragmentsPhenylephrineProto-Oncogene MasPyridinesReceptor, Angiotensin, Type 1Receptors, BradykininAngiotensinc-GMP,EndotheliumKidneyRenal artery

Identifiers

PMID28192151
PMCPMC6688182
OpenAlexW2587514028

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.