Evidence map›Paper›PMID 28191547›Full record

ArticleInternational journal of immunotherapy and cancer research2016

Significance of Cancer Stem Cells in Anti-Cancer Therapies.

Mónica Botelho, Helena Alves

Abstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of immunotherapy and cancer research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Drug Resistance Driven by Cancer Stem Cells and Their Niche.International journal of molecular sciences · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mónica BotelhoINSA, National Institute of Health Dr. Ricardo Jorge, Department of Health Promotion and Chronic Diseases, Rua Alexandre Herculano, Porto, Portugal; I3S, Instituto de Investigação e Inovação da Universidade do Porto, Portugal.
Helena AlvesINSA, National Institute of Health Dr. Ricardo Jorge, Department of Health Promotion and Chronic Diseases, Rua Alexandre Herculano, Porto, Portugal; Fundação Professor Ernesto Morais, Porto, Portugal.

Funding

Role of Cancer Stem Cells in Malignant Progression of Ductal Carcinoma in Situ.K99CA127462 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BEHBOD, FARIBA · 2007 to 2008
$272k
Stem CellsR13GM076902 · NIGMS · KEYSTONE SYMPOSIA · PI VERFAILLIE, CATHERINE M · 2005 to 2006
$17k
NCI NIH HHS K99 CA127462NIGMS NIH HHS R13 GM076902
6 · The paper itself

Abstract

Stem cells are the focus of cutting edge research interest because of their competence both to self-renew and proliferate, and to differentiate into a variety of tissues, offering enticing prospects of growing replacement organs in vitro, among other possible therapeutic implications. It is conceivable that cancer stem cells share a number of biological hallmarks that are different from their normal-tissue counterparts and that these might be taken advantage of for therapeutic benefits. In this review we discuss the significance of cancer stem cells in diagnosis and prognosis of cancer as well as in the development of new strategies for anti-cancer drug design.

Indexed as

Anti-cancer therapiesCancerStem cell markersStem cells

Identifiers

PMID28191547
PMCPMC5298826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.