Evidence map›Paper›PMID 28191433›Full record

ReviewNano convergence2016

Multidimensional nanomaterials for the control of stem cell fate.

Sy-Tsong Dean Chueng, Letao Yang, Yixiao Zhang, Ki-Bum Lee

Abstract readReview
In one paragraph

Review in Nano convergence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Engineering molecular imaging strategies for regenerative medicine.Bioengineering & translational medicine · 2018
    Review
  8. Article
  9. Applications of Nanosheets in Frontier Cellular Research.Nanomaterials (Basel, Switzerland) · 2018
    Review
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sy-Tsong Dean ChuengDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854 USA.
Letao YangDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854 USA.
Yixiao ZhangDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854 USA.
Ki-Bum LeeDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854 USA.

Funding

Combinatorial approaches for studying multiple cues regulating human pluripotentDP2OD006462 · OD · RUTGERS, THE STATE UNIV OF N.J. · PI LEE, KIBUM · 2009 to 2009
$2.3M
Novel magnetic core/shell nanoparticle-based stem cell therapy to direct neural sR21NS085569 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI LEE, KIBUM · 2013 to 2014
$421k
NIH HHS DP2 OD006462NINDS NIH HHS R21 NS085569
6 · The paper itself

Abstract

Current stem cell therapy suffers low efficiency in giving rise to differentiated cell lineages, which can replace the original damaged cells. Nanomaterials, on the other hand, provide unique physical size, surface chemistry, conductivity, and topographical microenvironment to regulate stem cell differentiation through multidimensional approaches to facilitate gene delivery, cell-cell, and cell-ECM interactions. In this review, nanomaterials are demonstrated to work both alone and synergistically to guide selective stem cell differentiation. From three different nanotechnology families, three approaches are shown: (1) soluble microenvironmental factors; (2) insoluble physical microenvironment; and (3) nano-topographical features. As regenerative medicine is heavily invested in effective stem cell therapy, this review is inspired to generate discussions in the potential clinical applications of multi-dimensional nanomaterials.

Indexed as

BiomaterialsDifferentiationElectrospun nanofibersGrapheneNanoparticlesStem cells

Identifiers

PMID28191433
PMCPMC5271342

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.