Evidence map›Paper›PMID 28190636›Full record

Trial reportClinical oncology (Royal College of Radiologists (Great Britain))2017

Correlation of

J M Wilson, S Mukherjee, T B Brunner, M Partridge, M A Hawkins

Abstract readClinical Trial, Phase II
In one paragraph

Trial report in Clinical oncology (Royal College of Radiologists (Great Britain)), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. [Scientific reports · 2022
    Article
  5. Article
  6. Radiolabeled cCPE Peptides for SPECT Imaging of Claudin-4 Overexpression in Pancreatic Cancer.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. A Review of Pancreatic Cancer: Epidemiology, Genetics, Screening, and Management.Open access Macedonian journal of medical sciences · 2019
    Review
  12. Translational molecular imaging in exocrine pancreatic cancer.European journal of nuclear medicine and molecular imaging · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J M WilsonCRUK/MRC Oxford Institute for Radiation Oncology, Gray Laboratories, Oxford, UK. Electronic address: james.wilson@icr.ac.uk.
S MukherjeeCRUK/MRC Oxford Institute for Radiation Oncology, Gray Laboratories, Oxford, UK.
T B BrunnerDepartment of Radiation Oncology, University Hospitals Freiburg, Freiburg im Breisgau, Germany.
M PartridgeCRUK/MRC Oxford Institute for Radiation Oncology, Gray Laboratories, Oxford, UK.
M A HawkinsCRUK/MRC Oxford Institute for Radiation Oncology, Gray Laboratories, Oxford, UK.

Funding

Cancer Research UK 16049Cancer Research UK 16466
6 · The paper itself

Abstract

aimsA proportion of patients with pancreatic cancer never develop metastatic disease. We evaluated a role for MATERIAL AND

methodsPatients with histologically confirmed LAPC entered a single-centre phase II study of definitive upfront chemoradiotherapy (CRT). All patients underwent FDG-PET/CT before and 6 weeks after CRT. Tumour volume, standardised uptake values (SUV

resultsTwenty-three patients with LAPC were recruited; 17/23 completed treatment and had interpretable sequential imaging. Twenty-four per cent of patients only ever experienced local disease. Median pre-CRT FDG-PET parameters were significantly lower in patients with local disease only during follow-up compared with those who developed metastatic disease: SUV

conclusionsOur findings suggest that patients with less FDG-avid tumours are less likely to metastasise and may therefore benefit from upfront local treatment intensification.

Indexed as

Positron-Emission TomographyAdultAgedArea Under CurveChemoradiotherapyDisease ProgressionFemaleFluorodeoxyglucose F18GlycolysisHumansMaleMiddle AgedNeoplasm MetastasisPancreatic NeoplasmsPositron Emission Tomography Computed TomographyPredictive Value of TestsFluorodeoxyglucose F18RadiopharmaceuticalsChemoradiotherapyFDG-PETpancreatic cancertreatment strategy selection

Identifiers

PMID28190636
PMCPMC5429392

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.