ArticleEpidemiology and infection2017
Determinants of mortality in elderly patients with tuberculosis: a population-based follow-up study.
Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Factors associated with severity of pulmonary tuberculosis in people living with and without HIV: a systematic review.BMC infectious diseases · 2026Pooled it
- Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies.PLoS medicine · 2018Pooled it
- Host immunosenescence compromisesAging · 2026Article
- Article
- Predictive analysis of all-cause mortality of previously untreated pulmonary tuberculosis patients complicated by hypertension.Frontiers in cellular and infection microbiology · 2025Article
- Trends in Drug Resistance and Epidemiological Patterns of Tuberculosis in Elderly Patients in Wenzhou, China (2014-2023).Infection and drug resistance · 2025Article
- High all-cause mortality and increasing proportion of older adults with tuberculosis in Texas, 2008-2020.Epidemiology and infection · 2024Article
- Factors associated with adverse drug reactions or death in very elderly hospitalized patients with pulmonary tuberculosis.Scientific reports · 2023Article
- Post-discharge mortality in adult patients hospitalized for tuberculosis: a prospective cohort study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023Article
- Tuberculosis in elderly: Epidemiological profile, prognosis factors and chronological trends in Southern Tunisia, 1995-2016.Journal of infection prevention · 2022Article
- Predictors for Pulmonary Tuberculosis Outcome and Adverse Events in an Italian Referral Hospital: A Nine-Year Retrospective Study (2013-2021).Annals of global health · 2022Article
- Tuberculosis Death Epidemiology and Its Associated Risk Factors in Sabah, Malaysia.International journal of environmental research and public health · 2021Article
- Safety of Pyrazinamide for the Treatment of Tuberculosis in Older Patients Over 75 Years of Age: A Retrospective Monocentric Cohort Study.Drugs & aging · 2021Article
- The Relationship Between Socio-Demographic Factors and Tuberculosis Mortality in the Republic of Korea During 2008-2017.Frontiers in public health · 2021Article
- Detection of risk clusters for deaths due to tuberculosis specifically in areas of southern Brazil where the disease was supposedly a non-problem.BMC infectious diseases · 2019Article
- Tuberculosis mortality and associated factors at King Abdulaziz Medical City Hospital.BMC infectious diseases · 2019Article
- Clinical significance of Glasgow Prognostic Score in patients with tuberculous pleurisy.Journal of thoracic disease · 2018Article
- Depressed Gamma Interferon Responses and Treatment Outcomes in Tuberculosis Patients: a Prospective Cohort Study.Journal of clinical microbiology · 2018Article
- Treatment delay and fatal outcomes of pulmonary tuberculosis in advanced age: a retrospective nationwide cohort study.BMC infectious diseases · 2017Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elderly individuals with tuberculosis (TB) are more likely to have a non-specific clinical presentation of TB and high mortality. However, factors associated with mortality in elderly TB patients have not been extensively studied. This retrospective cohort study aimed to identify factors associated with death among elderly Taiwanese with TB. All elderly patients with TB from 2006 to 2014 in Taipei, Taiwan, were included in a study. Multiple logistic regression was used to identify the factors associated with death in elderly TB patients. The mean age of the 5011 patients was 79·7 years; 74·1% were men; 32·7% had mortality during the study follow-up period. After controlling for potential confounders, age ⩾75 years (reference: 65-74 years), male sex, end-stage renal disease (ESRD), malignancy, acid-fast bacilli-smear positivity, TB-culture positivity, pleural effusion on chest radiograph and notification by an ordinary ward or intensive care unit were associated with a higher risk of all-cause death; while high school, and university or higher education, cavity on chest radiograph and directly observed therapy were associated with a lower risk of all-cause death. This study found that the proportion of death among elderly patients with TB in Taipei, Taiwan, was high. To improve TB treatment outcomes, future control programmes should particularly target individuals with comorbidities (e.g. ESRD and malignancy) and those with a lower socio-economic status (e.g. not educated).
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