ArticleGenome biology2017
Rapid transcriptional plasticity of duplicated gene clusters enables a clonally reproducing aphid to colonise diverse plant species.
Article in Genome biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 100 papers.
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100 citing papers in PubMed, 837 citations in OpenAlex.
- Epidemiological drivers of turnip yellows virus and its vector Myzus persicae in Australian canola (Brassica napus) systems: a 3-year study of commercial crops and noncrop vegetation.Pest management science · 2026Article
- Non-consumptive effects of Harmonia axyridis (Coleoptera: Coccinellidae) derived semiochemicals on Myzus persicae (Hemiptera: Aphididae).Journal of insect science (Online) · 2026Article
- Challenges in Aphid Pest Management Including Global Case Studies and Prospects.Plants (Basel, Switzerland) · 2026Review
- Chromosome-level genome assembly of the bird cherry-oat aphid, Rhopalosiphum padi (Hemiptera: Aphididae).Scientific data · 2026Article
- Transcriptome analysis and characterization of cathepsin B-like protein inMolecular breeding : new strategies in plant improvement · 2026Article
- Chromosome-level genome assembly of a citrus and tea insect pest, Aphis aurantii.Scientific data · 2026Article
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- Comprehensive Analysis of Cathepsin Genes in Hemiptera: Functional Characterization of the Venomous Cathepsin B fromInsects · 2025Article
- Aphid effector Mp10 balances immune suppression and defence activation through EDS1-dependent modulation of plant DAMP responses.The New phytologist · 2025Article
- Chromosome-level genome assembly of vetch aphid Megoura crassicauda (Hemiptera: Aphididae).Scientific data · 2025Article
- Chromosome scale genomes of two invasive Adelges species enable virtual screening for selective adelgicides.bioRxiv : the preprint server for biology · 2025Article
- Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodies.Science advances · 2025Article
- A-to-I RNA editing ofeLife · 2025Article
- Host plant flooding stress in soybeans differentially impacts avirulent and virulent soybean aphid (Aphis glycines) biotypes.Scientific reports · 2025Article
- A chromosome-level genome assembly of the cabbage aphid Brevicoryne brassicae.Scientific data · 2025Article
- Multi-omics approaches define novel aphid effector candidates associated with virulence and avirulence phenotypes.BMC genomics · 2024Article
- Azooxanthellate Palythoa (Cnidaria: Anthozoa) Genomes Reveal Toxin-related Gene Clusters and Loss of Neuronal Genes in Hexacorals.Genome biology and evolution · 2024Article
- Article
- A chromosome-level genome assembly of the Rhus gall aphid Schlechtendalia chinensis provides insight into the endogenization of Parvovirus-like DNA sequences.BMC genomics · 2024Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
36 authors at 16 institutions in 4 countries.
Funding
Abstract
backgroundThe prevailing paradigm of host-parasite evolution is that arms races lead to increasing specialisation via genetic adaptation. Insect herbivores are no exception and the majority have evolved to colonise a small number of closely related host species. Remarkably, the green peach aphid, Myzus persicae, colonises plant species across 40 families and single M. persicae clonal lineages can colonise distantly related plants. This remarkable ability makes M. persicae a highly destructive pest of many important crop species.
resultsTo investigate the exceptional phenotypic plasticity of M. persicae, we sequenced the M. persicae genome and assessed how one clonal lineage responds to host plant species of different families. We show that genetically identical individuals are able to colonise distantly related host species through the differential regulation of genes belonging to aphid-expanded gene families. Multigene clusters collectively upregulate in single aphids within two days upon host switch. Furthermore, we demonstrate the functional significance of this rapid transcriptional change using RNA interference (RNAi)-mediated knock-down of genes belonging to the cathepsin B gene family. Knock-down of cathepsin B genes reduced aphid fitness, but only on the host that induced upregulation of these genes.
conclusionsPrevious research has focused on the role of genetic adaptation of parasites to their hosts. Here we show that the generalist aphid pest M. persicae is able to colonise diverse host plant species in the absence of genetic specialisation. This is achieved through rapid transcriptional plasticity of genes that have duplicated during aphid evolution.
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