ArticleTobacco control2018
Identification of flavour additives in tobacco products to develop a flavour library.
Article in Tobacco control, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Flavor-Toxicant Correlation in E-cigarettes: A Meta-Analysis.Chemical research in toxicology · 2020Pooled it
- Velo (BAT) buffet of oral nicotine pouches in Pakistan: varying brand variant levels of nicotine, menthol and other flavour chemicals.Tobacco control · 2026Article
- Dynamic multi-omics analysis reveals the correlation between aroma compounds and symbiotic microbial community during tobacco leaf aging process.BMC plant biology · 2025Article
- Effect of microbial community on the formation of flavor components in cigar tobacco leaves during air-curing.BMC microbiology · 2025Article
- Unraveling the microbiome-aroma Nexus: a metagenomic and volatile compound analysis of Yunnan cigars.Frontiers in microbiology · 2025Article
- Metagenomic insight into the biodegradation of biomass and alkaloids in the aging process of cigar.Bioresources and bioprocessing · 2023Article
- Interaction analysis of tobacco leaf microbial community structure and volatiles flavor compounds during cigar stacking fermentation.Frontiers in microbiology · 2023Article
- How Do Herbal Cigarettes Compare To Tobacco? A Comprehensive Review of Their Sensory Characters, Phytochemicals, and Functional Properties.ACS omega · 2022Review
- Impairment of Endothelial Function by Cigarette Smoke Is Not Caused by a Specific Smoke Constituent, but by Vagal Input From the Airway.Arteriosclerosis, thrombosis, and vascular biology · 2022Article
- Dissonance in Young Adult Cigarillo Users' Categorization of Concept Flavored and Unflavored Products.International journal of environmental research and public health · 2022Article
- RETRACTED: Measuring Liquid Droplet Size in Two-Phase Nozzle Flow Employing Numerical and Experimental Analyses.Micromachines · 2022Article
- The Flavor Train: The Nature and Extent of Flavored Cigarettes in Low- and Middle-Income Countries.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021Article
- 9. Flavours in novel and emerging nicotine and tobacco products.World Health Organization technical report series · 2021Article
- New Analytical Method for Quantifying Flavoring Chemicals of Potential Respiratory Health Risk Concerns in e-Cigarette Liquids.Frontiers in chemistry · 2021Article
- Transitions from and to roll-your-own tobacco, perceptions and health beliefs among smokers: findings from the EUREST-PLUS ITC Europe Surveys.European journal of public health · 2020Article
- Sensory analysis of characterising flavours: evaluating tobacco product odours using an expert panel.Tobacco control · 2019Article
- Classification of flavors in cigarillos and little cigars and their variable cellular and acellular oxidative and cytotoxic responses.PloS one · 2019Article
- Should flavours be banned in cigarettes and e-cigarettes? Evidence on adult smokers and recent quitters from a discrete choice experiment.Tobacco control · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study combines chemical analysis and flavour descriptions of flavour additives used in tobacco products, and provides a starting point to build an extensive library of flavour components, useful for product surveillance.
methodsHeadspace gas chromatography-mass spectrometry (GC-MS) was used to compare 22 commercially available tobacco products (cigarettes and roll-your-own) expected to have a characterising flavour and 6 commercially available products not expected to have a characterising flavour with 5 reference products (natural tobacco leaves and research cigarettes containing no flavour additives). The flavour components naturally present in the reference products were excluded from components present in commercially available products containing flavour additives. A description of the remaining flavour additives was used for categorisation.
resultsGC-MS measurements of the 33 tobacco products resulted in an overview of 186 chemical compounds. Of these, 144 were solely present in commercially available products. These 144 flavour additives were described using 62 different flavour descriptors extracted from flavour databases, which were categorised into eight groups largely based on the definition of characterising flavours from the European Tobacco Product Directive: fruit, spice, herb, alcohol, menthol, sweet, floral and miscellaneous.
conclusionsWe developed a method to identify and describe flavour additives in tobacco products. Flavour additives consist of single flavour compounds or mixtures of multiple flavour compounds, and different combinations of flavour compounds can cause a certain flavour. A flavour library helps to detect flavour additives that are characteristic for a certain flavour, and thus can be useful for regulation of flavours in tobacco and related products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.