ArticleThe Journal of experimental medicine2017
Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome.
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Article in The Journal of experimental medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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0cells of the map it votes in
24citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
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Who cites it
24 citing papers in PubMed, 37 citations in OpenAlex.
- mTORC1 inhibition upregulates CD20 and enhances anti-CD20 antibody efficacy in B-cell precursor acute lymphoblastic leukemia.Leukemia · 2026Article
- A specific stem cell program and CD112 immunological axis dysfunctions underpinning monosomy 7-associated myeloid neoplasms.Signal transduction and targeted therapy · 2026Article
- Insights into the biological features and improved diagnostics of adult acute myeloid leukemia via fusion genes identified through targeted next-generation sequencing.Cancer pathogenesis and therapy · 2026Article
- Comment on "Acute pro-B-cell lymphoblastic leukemia evolving from myelodysplastic neoplasm post cytotoxic therapy: a case report".Haematologica · 2025Article
- Adaptor protein Abelson interactor 1 in homeostasis and disease.Cell communication and signaling : CCS · 2024Review
- The advances of E2A-PBX1 fusion in B-cell acute lymphoblastic Leukaemia.Annals of hematology · 2024Review
- Concepts in B cell acute lymphoblastic leukemia pathogenesis.Journal of leukocyte biology · 2024Review
- IKAROS Family Transcription Factors in Lymphocyte Differentiation and Function.Advances in experimental medicine and biology · 2024Review
- IKAROS in Acute Leukemia: A Positive Influencer or a Mean Hater?International journal of molecular sciences · 2023Review
- Article
- Ikaros Regulates microRNA Networks in Acute Lymphoblastic Leukemia.Epigenomes · 2022Article
- RAG enhances BCR-ABL1-positive leukemic cell growth through its endonuclease activity in vitro and in vivo.Cancer science · 2021Article
- Focused CRISPR-Cas9 genetic screening reveals USO1 as a vulnerability in B-cell acute lymphoblastic leukemia.Scientific reports · 2021Article
- Prognostic Relevance of Expression ofFrontiers in oncology · 2021Article
- Article
- Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia.Cancer cell · 2020Article
- Whole-genome analysis uncovers recurrent IKZF1 inactivation and aberrant cell adhesion in blastic plasmacytoid dendritic cell neoplasm.Genes, chromosomes & cancer · 2020Article
- Malignancy and IFITM3: Friend or Foe?Frontiers in oncology · 2020Review
- Aberrant X chromosome skewing and acquired clonal hematopoiesis in adult-onset common variable immunodeficiency.JCI insight · 2019Article
- Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation.PLoS biology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 9 institutions in 4 countries.
Matthew T WitkowskiAustralian Centre for Blood Diseases, Monash University, Melbourne, Victoria 3004, Australia.ORCID 0000-0002-5019-0119
Yifang HuBioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.ORCID 0000-0001-8200-0052
Kathryn G RobertsDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN 38105.
Judith M BoerDepartment of Pediatric Oncology, Erasmus MC - Sophia Children's Hospital, 3015 CN Rotterdam, Netherlands.
Mark D McKenzieMolecular Medicine Division, Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.
Grace J LiuAustralian Centre for Blood Diseases, Monash University, Melbourne, Victoria 3004, Australia.
Oliver D Le GriceAustralian Centre for Blood Diseases, Monash University, Melbourne, Victoria 3004, Australia.ORCID 0000-0001-5557-769X
Cedric S TremblayAustralian Centre for Blood Diseases, Monash University, Melbourne, Victoria 3004, Australia.ORCID 0000-0003-2396-776X
Margherita GhisiAustralian Centre for Blood Diseases, Monash University, Melbourne, Victoria 3004, Australia.
Tracy A WillsonMolecular Medicine Division, Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.ORCID 0000-0003-4833-7342
Martin A HorstmannResearch Institute Children's Cancer Center, Department of Pediatric Hematology and Oncology, University Medical Center Hamburg, 20246 Hamburg, Germany.ORCID 0000-0001-8559-8862
Iannis AifantisDepartment of Pathology, NYU School of Medicine, New York, NY 10016.
Luisa CimminoDepartment of Pathology, NYU School of Medicine, New York, NY 10016.ORCID 0000-0002-8729-6435
Seth FrietzeDepartment of Medical Laboratory and Radiation Science, University of Vermont, Burlington, VT 05405.
Monique L den BoerDepartment of Pediatric Oncology, Erasmus MC - Sophia Children's Hospital, 3015 CN Rotterdam, Netherlands.ORCID 0000-0002-5795-2921
Charles G MullighanDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN 38105.
Gordon K SmythBioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.ORCID 0000-0001-9221-2892
Ross A DickinsAustralian Centre for Blood Diseases, Monash University, Melbourne, Victoria 3004, Australia ross.dickins@monash.edu.ORCID 0000-0003-4112-5304
The University of Melbourne · AUWalter and Eliza Hall Institute of Medical Research · AUAustralian Centre for HIV and Hepatitis Virology Research · AUNew York University · USSt. Jude Children's Research Hospital · USErasmus MC - Sophia Children’s Hospital · NLStichting Kinderoncologie Nederland · NLUniversität Hamburg · DEUniversity of Vermont Medical Center · US
Funding
Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9MGENOMIC ANALYSIS OF ADOLESCENT AND YOUNG ADULT ACUTE LYMPHOBLASTIC LEUKEMIARC1CA145707 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI MULLIGHAN, CHARLES G., WILLMAN, CHERYL LYNN · 2009 to 2010
$1.0MNCI NIH HHS P30 CA021765NCI NIH HHS RC1 CA145707
Abstract
Genetic alterations disrupting the transcription factor
Indexed as
AnimalsCateninsCell Line, TumorDelta CateninFusion Proteins, bcr-ablHumansIkaros Transcription FactorMembrane ProteinsMiceNeoplasm ProteinsPrecursor B-Cell Lymphoblastic Leukemia-LymphomaReceptors, Cell SurfaceRNA-Binding ProteinsBCR-ABL1 fusion protein, humanCateninsDelta Cateninepithelial membrane protein-1Fusion Proteins, bcr-ablIFITM3 protein, humanIkaros Transcription FactorMembrane ProteinsNeoplasm ProteinsReceptors, Cell SurfaceRNA-Binding Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.