Evidence map›Paper›PMID 28189613›Full record

ArticleNeuroscience2017

α4βδ GABA

Sonia Afroz, Hui Shen, Sheryl S Smith

Abstract read
In one paragraph

Article in Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. The role of GABANeuroscience and biobehavioral reviews · 2026
    Review
  3. Manipulation of α4βδ GABABrain research · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Allopregnanolone and reproductive psychiatry: an overview.International review of psychiatry (Abingdon, England) · 2019
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Sonia AfrozDepartment of Physiology and Pharmacology, SUNY Downstate Medical Center, 450 Clarkson Ave., Brooklyn, NY 11203, USA.
Hui ShenDepartment of Physiology and Pharmacology, SUNY Downstate Medical Center, 450 Clarkson Ave., Brooklyn, NY 11203, USA; School of Biomedical Engineering, Tianjin Medical University, No. 22 Qixiangtai Road, Heping District, Tianjin 300070, China.
Sheryl S SmithDepartment of Physiology and Pharmacology, SUNY Downstate Medical Center, 450 Clarkson Ave., Brooklyn, NY 11203, USA. Electronic address: sheryl.smith@downstate.edu.
SUNY Downstate Health Sciences University · US

Funding

Functional consequences of GABAergic inhibition of dendritic spines at pubertyR01MH100561 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI SMITH, SHERYL S · 2013 to 2017
$3.0M
NIMH NIH HHS R01 MH100561
6 · The paper itself

Abstract

Synaptic pruning underlies the transition from an immature to an adult CNS through refinements of neuronal circuits. Our recent study indicates that pubertal synaptic pruning is triggered by the inhibition generated by extrasynaptic α4βδ GABA

Indexed as

AgingNeuronal PlasticityAnimalsCA1 Region, HippocampalDendritic SpinesFemaleGABA-A Receptor AgonistsIsoxazolesMiceMice, Inbred C57BLNeuronsPregnanoloneReceptors, GABA-ASpatial LearningGABA-A Receptor AgonistsgaboxadolIsoxazolesPregnanoloneReceptors, GABA-Aallopregnanolonealpha4deltaGABA-A receptorgaboxadolsynaptic pruning

Identifiers

PMID28189613
PMCPMC5404891
OpenAlexW2587057685

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.