Evidence map›Paper›PMID 28189413›Full record

ArticleAmerican journal of infection control2017

Outcome of strict implementation of infection prevention control measures during an outbreak of Middle East respiratory syndrome.

Hassan E El Bushra, Hussain A Al Arbash, Mutaz Mohammed, Osman Abdalla, Mohamed N Abdallah, Zayid K Al-Mayahi, Abdallah M Assiri, Abdulaziz A BinSaeed

Abstract read
In one paragraph

Article in American journal of infection control, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Review
  12. A proposal for the eradication of Middle East respiratory syndrome.American journal of infection control · 2017
    Article
  13. Control of Middle East respiratory syndrome.American journal of infection control · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Hassan E El BushraField Epidemiology Training Program, Ministry of Health, Riyadh, Saudi Arabia. Electronic address: bestregards.h@gmail.com.
Hussain A Al ArbashField Epidemiology Training Program, Ministry of Health, Riyadh, Saudi Arabia.
Mutaz MohammedGeneral Directorate for Control of Communicable Disease, Ministry of Health, Riyadh, Saudi Arabia.
Osman AbdallaGeneral Directorate for Control of Communicable Disease, Ministry of Health, Riyadh, Saudi Arabia.
Mohamed N AbdallahField Epidemiology Training Program, Ministry of Health, Riyadh, Saudi Arabia.
Zayid K Al-MayahiField Epidemiology Training Program, Ministry of Health, Riyadh, Saudi Arabia.
Abdallah M AssiriDeputyship for Public Health, Ministry of Health, Riyadh, Saudi Arabia.
Abdulaziz A BinSaeedDeputyship for Public Health, Ministry of Health, Riyadh, Saudi Arabia; King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this retrospective cohort study was to assess the impact of implementation of different levels of infection prevention and control (IPC) measures during an outbreak of Middle East respiratory syndrome (MERS) in a large tertiary hospital in Saudi Arabia. The setting was an emergency room (ER) in a large tertiary hospital and included primary and secondary MERS patients.

methodsRapid response teams conducted repeated assessments of IPC and monitored implementation of corrective measures using a detailed structured checklist. We ascertained the epidemiologic link between patients and calculated the secondary attack rate per 10,000 patients visiting the ER (SAR/10,000) in 3 phases of the outbreak.

resultsIn phase I, 6 primary cases gave rise to 48 secondary cases over 4 generations, including a case that resulted in 9 cases in the first generation of secondary cases and 21 cases over a chain of 4 generations. During the second and third phases, the number of secondary cases sharply dropped to 18 cases and 1 case, respectively, from a comparable number of primary cases. The SAR/10,000 dropped from 75 (95% confidence interval [CI], 55-99) in phase I to 29 (95% CI, 17-46) and 3 (95% CI, 0-17) in phases II and III, respectively.

conclusionsThe study demonstrated salient evidence that proper institution of IPC measures during management of an outbreak of MERS could remarkably change the course of the outbreak.

Indexed as

Disease OutbreaksCoronavirus InfectionsCross InfectionDisease Transmission, InfectiousHumansInfection ControlRetrospective StudiesSaudi ArabiaTertiary Care CentersImpactInfection prevention and control (IPC)Middle East Respiratory Syndrome (MERS)OutbreakSaudi ArabiaSecondary attack rate

Identifiers

PMID28189413
PMCPMC7132728

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.