Evidence map›Paper›PMID 28188395›Full record

ArticleInternational orthopaedics2017

Marshall R. Urist and the discovery of bone morphogenetic proteins.

Lovorka Grgurevic, Marko Pecina, Slobodan Vukicevic

Abstract readBiographyHistorical Article
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Low-Intensity Pulsed Ultrasound Promotes Osteogenesis in Porous Titanium Alloys Through miR-1187/BMP4 Pathway.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
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  5. Review
  6. Article
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  8. Article
  9. Article
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  11. Article
  12. Review
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  15. Evaluation of Demineralized Bone Matrix Particles Delivered by Alginate Hydrogel for a Bone Graft Substitute: An Animal Experimental Study.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Article
  16. Review
  17. Article
  18. Review
  19. Bone morphogenetic proteins in fracture repair.International orthopaedics · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lovorka GrgurevicLaboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, Salata 11, 10000, Zagreb, Croatia. lgrgurev@mef.hr.
Marko PecinaDepartment of Orthopaedic Surgery, School of Medicine, University of Zagreb, Salata 11, 10000, Zagreb, Croatia.
Slobodan VukicevicLaboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, Salata 11, 10000, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last 40 years International Orthopaedics has published a series of articles on bone morphogenetic proteins (BMPs) covering topics from basic research to clinical applications. This includes also work submitted from the Laboratory for Mineralized Tissues of the School of Medicine University of Zagreb. Accordingly, we felt obliged to give a short summary of Dr. Urist's life and work as our gratitude to his discovery that demineralized bone matrix (DBM) activity induces bone when implanted ectopically into the muscle or under the skin due to bone inducing proteins, named BMPs.

Indexed as

Bone and BonesBone Morphogenetic ProteinsAged, 80 and overHistory, 20th CenturyHistory, 21st CenturyHumansMaleMedicineBone Morphogenetic ProteinsBone morphogenetic proteinsBone regenerationHeterotopic ossificationMarshall Urist

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.