ArticleJournal of immunology (Baltimore, Md. : 1950)2017
Cutting Edge: The Transcription Factor Sox2 Regulates AID Expression in Class-Switched B Cells.
Lauren J DiMenna, Wei-Feng Yen, Laura Nicolas, Rahul Sharma, Zara N Saldanha, Jayanta Chaudhuri
Open access · bronzeAbstract read
In one paragraphArticle in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
6 authors at 1 institution in 1 country.
Lauren J DiMennaImmunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021; and.
Wei-Feng YenImmunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021; and.
Laura NicolasImmunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021; and.
Rahul SharmaImmunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021; and.
Jayanta ChaudhuriImmunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021; and chaudhuj@mskcc.org.ORCID 0000-0002-3838-0075 Memorial Sloan Kettering Cancer Center · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4MMechanistic Elucidation of Class Switch Recombination and Somatic HypermutationR01AI072194 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI CHAUDHURI, JAYANTA · 2009 to 2025
$6.9MRNA-directed targeting of AID in immunity and genomic integrityR01AI124186 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI Jayanta Chaudhuri · 2016 to 2026
$4.8MMechanistic Elucidation of Class Switch Recombination and Somatic HypermutationR56AI072194 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI CHAUDHURI, JAYANTA · 2020 to 2020
$531kNCI NIH HHS P30 CA008748NIAID NIH HHS R01 AI072194NIAID NIH HHS R01 AI124186NIAID NIH HHS R56 AI072194
6 · The paper itselfAbstract
IgH class switch recombination (CSR) occurs through the deliberate introduction of activation-induced cytidine deaminase (AID)-instigated DNA double-strand breaks into the
Indexed as
AICDA (Activation-Induced Cytidine Deaminase)AnimalsB-LymphocytesCell DifferentiationCells, CulturedCytidine DeaminaseDNA Breaks, Double-StrandedGenes, mycGenomic InstabilityImmunoglobulin Switch RegionLymphocyte ActivationMiceMice, Inbred C57BLMice, KnockoutSOXB1 Transcription FactorsSpleenAICDA (Activation-Induced Cytidine Deaminase)Cytidine DeaminaseSox2 protein, mouseSOXB1 Transcription Factors
Identifiers
PMID28188246
PMCPMC5373658
OpenAlexW2602377636
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390