Evidence map›Paper›PMID 28188224›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2017

Lung pericyte-like cells are functional interstitial immune sentinel cells.

Chi F Hung, Kristen L Mittelsteadt, Rena Brauer, Bonnie L McKinney, Teal S Hallstrand, William C Parks, Peter Chen, Lynn M Schnapp, W Conrad Liles, Jeremy S Duffield and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 58 citations in OpenAlex.

  1. Pericytes and Lung Vascular Remodeling.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Stromal heterogeneity in the adult lung delineated by single-cell genomics.American journal of physiology. Cell physiology · 2025
    Review
  6. Review
  7. Article
  8. Pericytes mediate neuroinflammation via Fli-1 in endotoxemia and sepsis in mice.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  9. MULTIFACETED ROLES OF PERICYTES IN LUNG INJURY AND REPAIR.Transactions of the American Clinical and Climatological Association · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Lung pericytes as mediators of inflammation.American journal of physiology. Lung cellular and molecular physiology · 2023
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Effect of lung pericyte-like cell ablation on the bleomycin model of injury and repair.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Chi F HungCenter for Lung Biology, Department of Medicine, University of Washington, Seattle, Washington.
Kristen L MittelsteadtCenter for Lung Biology, Department of Medicine, University of Washington, Seattle, Washington.
Rena BrauerCenter for Lung Biology, Department of Medicine, University of Washington, Seattle, Washington.
Bonnie L McKinneyDepartment of Pathology, University of Washington, Seattle, Washington.
Teal S HallstrandCenter for Lung Biology, Department of Medicine, University of Washington, Seattle, Washington.
William C ParksCenter for Lung Biology, Department of Medicine, University of Washington, Seattle, Washington.
Peter ChenCenter for Lung Biology, Department of Medicine, University of Washington, Seattle, Washington.
Lynn M SchnappCenter for Lung Biology, Department of Medicine, University of Washington, Seattle, Washington.
W Conrad LilesCenter for Lung Biology, Department of Medicine, University of Washington, Seattle, Washington.
Jeremy S DuffieldDivision of Nephrology, Department of Medicine, University of Washington, Seattle, Washington.
William A AltemeierCenter for Lung Biology, Department of Medicine, University of Washington, Seattle, Washington; billa@uw.edu.
University of Washington · US

Funding

Syndecan-1 in Lung RepairR01HL103868 · NHLBI · UNIVERSITY OF WASHINGTON · PI CHEN, PETER · 2011 to 2015
$2.1M
PDGFR-beta+ stromal cells as critical regulators of immune response to tissue injuryR01HL122895 · NHLBI · UNIVERSITY OF WASHINGTON · PI ALTEMEIER, WILLIAM A · 2015 to 2018
$1.7M
Role of integrin alpha 8 in resolution of lung injury and repairK08HL127075 · NHLBI · UNIVERSITY OF WASHINGTON · PI HUNG, CHI F · 2015 to 2019
$778k
NHLBI NIH HHS K08 HL127075NHLBI NIH HHS R01 HL103868NHLBI NIH HHS R01 HL122895
6 · The paper itself

Abstract

Pericytes are perivascular PDGF receptor-β

Indexed as

AnimalsBronchoalveolar Lavage FluidCells, CulturedImmune SystemInflammationInflammation MediatorsLungLung InjuryMice, Inbred C57BLMice, TransgenicModels, BiologicalPericytesReceptor, Platelet-Derived Growth Factor betaStromal CellsInflammation MediatorsReceptor, Platelet-Derived Growth Factor betaacute lung injurydamage-associated molecular patternsinflammationinnate immunitypericytes

Identifiers

PMID28188224
PMCPMC5407093
OpenAlexW2586389729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.