Evidence map›Paper›PMID 28187760›Full record

ArticleBMC neurology2017

Case report: subacute tetraplegia in an immunocompromised patient.

Daniel Zeller, Anke Heidemeier, Götz Ulrich Grigoleit, Wolfgang Müllges

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daniel ZellerDepartment of Neurology, University of Würzburg, Josef-Schneider-Str. 11, 97080, Würzburg, Germany. zeller_d@ukw.de.ORCID http://orcid.org/0000-0003-3393-5657
Anke HeidemeierDepartment of Radiology, University of Würzburg, Josef-Schneider-Str. 11, 97080, Würzburg, Germany.
Götz Ulrich GrigoleitDepartment of Internal Medicine II, University of Würzburg, 97080, Würzburg, Germany.
Wolfgang MüllgesDepartment of Neurology, University of Würzburg, Josef-Schneider-Str. 11, 97080, Würzburg, Germany.
University of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical reasoning in Neurology is based on general associations which help to deduce the site of the lesion. However, even "golden principles" may occasionally be deceptive. Here, we describe the case of subacute flaccid tetraparesis due to motor cortical lesions. To our knowledge, this is the first report to include an impressive illustration of nearly symmetric motor cortical involvement of encephalitis on brain MRI. CASE PRESENTATION: A 51 year old immunocompromized man developed a high-grade pure motor flaccid tetraparesis over few days. Based on clinical presentation, critical illness polyneuromyopathy was suspected. However, brain MRI revealed symmetrical hyperintensities strictly limited to the subcortical precentral gyrus. An encephalitis, possibly due to CMV infection, turned out to be the most likely cause.

conclusionWhile recognition of basic clinical patterns is indispensable in neurological reasoning, awareness of central conditions mimicking peripheral nervous disease may be crucial to detect unsuspected, potentially treatable conditions.

Indexed as

Immunocompromised HostCytomegalovirus InfectionsEncephalitisHumansMagnetic Resonance ImagingMaleMiddle AgedQuadriplegiaCase reportCMV encephalitisMotor cortexTetraparesis

Identifiers

PMID28187760
PMCPMC5303231
OpenAlexW2586630059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.