ArticleBMC infectious diseases2017
Survival of people living with HIV who defaulted from tuberculosis treatment in a cohort, Recife, Brazil.
Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed.
- Relationship between medication use and non-attendance (missed appointment) from primary care visits among people with type 2 diabetes: The Japan Diabetes Outcome Intervention Trial-2 Large-Scale Trial 006 (J-DOIT2-LT006).Journal of diabetes investigation · 2025Trial
- Clinical Determinants Associated With Viral Load Count Among Adult TB/HIV Co-Infected Patients: A Linear Mixed-Effects Model Analysis.Advances in virology · 2025Article
- Article
- HIV and Substance Use in Latin America: A Scoping Review.International journal of environmental research and public health · 2022Article
- Mortality and survival of tuberculosis coinfected patients living with AIDS in São Paulo, Brazil: a 12-year cohort study.BMC infectious diseases · 2022Article
- Mortality and associated factors among adult patients on tuberculosis treatment in Tanzania: A retrospective cohort study.Journal of clinical tuberculosis and other mycobacterial diseases · 2021Article
- Structural Prediction and Mutational Analysis of Rv3906c Gene ofAdvances in bioinformatics · 2018Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTuberculosis is a serious public health problem worldwide. It is the leading cause of death amongst people living with HIV, and default from tuberculosis (TB) treatment in people living with HIV increases the probability of death. The aim of this study was to estimate the survival probability of people living with HIV who default treatment for TB compared to those who complete the treatment.
methodsThis was a longitudinal cohort study of people living with HIV, from June 2007 to December 2013 with two components: a retrospective (for those who started tuberculosis treatment before 2013 for whom failure (death) or censoring occurred before 2013), and prospective (those who started tuberculosis treatment at any time between 2007 and June 2013 and for whom death or censoring occurred after the beginning of 2013), at two referral hospitals for people living with HIV (Correia Picanço Hospital - HCP and at Hospital Universitário Oswaldo Cruz - HUOC), in Recife/PE. A total of 317 patients who initiated TB treatment were studied. Default from TB treatment was defined as any patient who failed to attend their pre-booked return appointment at the health center for more than 30 consecutive days, in accordance with Brazilian Ministry of Health recommendations.
resultsFrom a cohort of 2372 people living with HIV we analyzed 317 patients who had initiated TB treatment. The incidence of death was 5.6 deaths per 100 persons per year (CI 95% 4.5 to 7.08). Independent factors associated with death: default from TB treatment 3.65 HR (95% CI 2.28 to 5.83); CD4 < 200 cells/mm
conclusionThe probability of death in people living with HIV who default TB treatment is approximately four times greater when compared to those who do not default from treatment.
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