ArticleBMC genomics2017
The abundance of homoeologue transcripts is disrupted by hybridization and is partially restored by genome doubling in synthetic hexaploid wheat.
Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- DNA methylation around transcription start sites is not globally associated with transcription in the grain of natural and synthetic hexaploid wheat.BMC plant biology · 2026Article
- Article
- Low impact of polyploidization on the transcriptome of synthetic allohexaploid wheat.BMC genomics · 2023Article
- Comparative analysis of Fusarium crown rot resistance in synthetic hexaploid wheats and their parental genotypes.BMC genomics · 2023Article
- Applications of In Vitro Tissue Culture Technologies in Breeding and Genetic Improvement of Wheat.Plants (Basel, Switzerland) · 2022Review
- PolyReco: A Method to Automatically Label Collinear Regions and Recognize Polyploidy Events Based on theFrontiers in genetics · 2022Article
- The Transcriptional and Splicing Changes Caused by Hybridization Can Be Globally Recovered by Genome Doubling during Allopolyploidization.Molecular biology and evolution · 2021Article
- Replaying the evolutionary tape to investigate subgenome dominance in allopolyploid Brassica napus.The New phytologist · 2021Article
- Reduced chromatin accessibility underlies gene expression differences in homologous chromosome arms of diploid Aegilops tauschii and hexaploid wheat.GigaScience · 2020Article
- Homoeolog expression bias and expression level dominance (ELD) in four tissues of natural allotetraploid Brassica napus.BMC genomics · 2020Article
- A transcriptomic view of the ability of nascent hexaploid wheat to tolerate aneuploidy.BMC plant biology · 2020Article
- The Resurgence of Introgression Breeding, as Exemplified in Wheat Improvement.Frontiers in plant science · 2020Review
- A breeding strategy targeting the secondary gene pool of bread wheat: introgression from a synthetic hexaploid wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Homoeolog expression bias and expression level dominance in resynthesized allopolyploid Brassica napus.BMC genomics · 2018Article
- Recent advances in understanding the roles of whole genome duplications in evolution.F1000Research · 2017Review
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Authors and funding
17 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe formation of an allopolyploid is a two step process, comprising an initial wide hybridization event, which is later followed by a whole genome doubling. Both processes can affect the transcription of homoeologues. Here, RNA-Seq was used to obtain the genome-wide leaf transcriptome of two independent Triticum turgidum × Aegilops tauschii allotriploids (F1), along with their spontaneous allohexaploids (S1) and their parental lines. The resulting sequence data were then used to characterize variation in homoeologue transcript abundance.
resultsThe hybridization event strongly down-regulated D-subgenome homoeologues, but this effect was in many cases reversed by whole genome doubling. The suppression of D-subgenome homoeologue transcription resulted in a marked frequency of parental transcription level dominance, especially with respect to genes encoding proteins involved in photosynthesis. Singletons (genes where no homoeologues were present) were frequently transcribed at both the allotriploid and allohexaploid plants.
conclusionsThe implication is that whole genome doubling helps to overcome the phenotypic weakness of the allotriploid, restoring a more favourable gene dosage in genes experiencing transcription level dominance in hexaploid wheat.
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