Evidence map›Paper›PMID 28187264›Full record

ArticleRadiology2017

Development of a Combined MR Fingerprinting and Diffusion Examination for Prostate Cancer.

Alice C Yu, Chaitra Badve, Lee E Ponsky, Shivani Pahwa, Sara Dastmalchian, Matthew Rogers, Yun Jiang, Seunghee Margevicius, Mark Schluchter, William Tabayoyong and 4 more

Abstract read
In one paragraph

Article in Radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Serial TEuropean radiology · 2026
    Article
  6. Article
  7. Prostate Diffusion-weighted Imaging: Selecting the Optimal Repetition Time Using Synthetic Imaging Techniques.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
  8. Article
  9. Article
  10. Clinical MR Biomarkers.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  11. Spatial image gradient estimation from the diffusion MRI profile.bioRxiv : the preprint server for biology · 2025
    Article
  12. Simultaneous liver TMagnetic resonance in medicine · 2025
    Article
  13. Article
  14. Quantitative Prostate MRI, From theAJR. American journal of roentgenology · 2025
    Review
  15. Article
  16. Time-resolved MR fingerprinting for TMagnetic resonance in medicine · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alice C YuFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Chaitra BadveFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Lee E PonskyFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Shivani PahwaFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Sara DastmalchianFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Matthew RogersFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Yun JiangFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Seunghee MargeviciusFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Mark SchluchterFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
William TabayoyongFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Robert AbouassalyFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Debra McGivneyFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Mark A GriswoldFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.
Vikas GulaniFrom the School of Medicine (A.C.Y., M.R.), Department of Radiology (C.B., S.P., S.D., M.A.G., V.G.), Department of Urology (L.E.P., W.T., R.A., V.G.), Department of Biomedical Engineering (Y.J., M.A.G., V.G.), Department of Epidemiology and Biostatistics (S.M., M.S.), and Department of Mathematics (D.M.), Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106.

Funding

The Cleveland Digestive Diseases Research Core Center (DDRCC)P30DK097948 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI Theresa Torres Pizarro · 2015 to 2026
$15.6M
Comprehensive quantitative ultrafast 3D liver MRIR01DK098503 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI GULANI, VIKAS, SEIBERLICH, NICOLE · 2013 to 2017
$2.6M
Optimization of MR Fingerprinting (MRF) for Quantitative MRIR01EB016728 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI GRISWOLD, MARK, GULANI, VIKAS · 2014 to 2017
$2.0M
NIBIB NIH HHS R01 EB016728NIDDK NIH HHS P30 DK097948NIDDK NIH HHS R01 DK098503
6 · The paper itself

Abstract

Purpose To develop and evaluate an examination consisting of magnetic resonance (MR) fingerprinting-based T1, T2, and standard apparent diffusion coefficient (ADC) mapping for multiparametric characterization of prostate disease. Materials and Methods This institutional review board-approved, HIPAA-compliant retrospective study of prospectively collected data included 140 patients suspected of having prostate cancer. T1 and T2 mapping was performed with fast imaging with steady-state precession-based MR fingerprinting with ADC mapping. Regions of interest were drawn by two independent readers in peripheral zone lesions and normal-appearing peripheral zone (NPZ) tissue identified on clinical images. T1, T2, and ADC were recorded for each region. Histopathologic correlation was based on systematic transrectal biopsy or cognitively targeted biopsy results, if available. Generalized estimating equations logistic regression was used to assess T1, T2, and ADC in the differentiation of (a) cancer versus NPZ, (b) cancer versus prostatitis, (c) prostatitis versus NPZ, and (d) high- or intermediate-grade tumors versus low-grade tumors. Analysis was performed for all lesions and repeated in a targeted biopsy subset. Discriminating ability was evaluated by using the area under the receiver operating characteristic curve (AUC). Results In this study, 109 lesions were analyzed, including 39 with cognitively targeted sampling. T1, T2, and ADC from cancer (mean, 1628 msec ± 344, 73 msec ± 27, and 0.773 × 10

Indexed as

AdultAgedBiopsyDiffusion Magnetic Resonance ImagingHumansMaleMiddle AgedProstatic NeoplasmsProstatitisRetrospective Studies

Identifiers

PMID28187264
PMCPMC5452885

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