ArticleJournal of acquired immune deficiency syndromes (1999)2017
Uptake of HIV Pre-Exposure Prophylaxis (PrEP) in a National Cohort of Gay and Bisexual Men in the United States.
Article in Journal of acquired immune deficiency syndromes (1999), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06159582 (eSTEP), which is not on this map. Cited by 210 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
eSTEP: An Integrated mHealth Intervention to Engage High-risk Individuals Along the Full PrEP Care Continuum
Who cites it
210 citing papers in PubMed, 2 syntheses or guidelines pooled it, 301 citations in OpenAlex.
- The experience of healthcare workers to HIV pre-exposure prophylaxis (PrEP) implementation in low- and middle-income countries: a systematic review and qualitative meta-synthesis.Frontiers in public health · 2023Pooled it
- A Systematic Review of the Social Network Strategy to Optimize HIV Testing in Key Populations to End the Epidemic in the United States.AIDS and behavior · 2021Pooled it
- Randomized Controlled Trial of a Group Cognitive Behavior Therapy HIV Prevention Intervention for Immigrant Latino Gay, Bisexual, and Other Men who Have Sex with Men.AIDS and behavior · 2026Trial
- Trial
- A stepped-wedge randomized trial and qualitative survey of HIV pre-exposure prophylaxis uptake in the Eswatini population.Science translational medicine · 2020Trial
- A Pilot Randomized Trial of Intervention Components Addressing Drug Use in Couples HIV Testing and Counseling (CHTC) with Male Couples.AIDS and behavior · 2019Trial
- Acute Alcohol Consumption Directly Increases HIV Transmission Risk: A Randomized Controlled Experiment.Journal of acquired immune deficiency syndromes (1999) · 2017Trial
- Expedited Partner Therapy (EPT) increases the frequency of partner notification among MSM in Lima, Peru: a pilot randomized controlled trial.BMC medicine · 2017Trial
- Applying the Transtheoretical Model and the Motivating PrEP Cascade to Better Understand the Correlates of Preexposure Prophylaxis (PrEP) Readiness Among Cisgender Black Women: A Correlational Study.Journal of racial and ethnic health disparities · 2026Article
- PrEP Use and Willingness Cascades Among Transgender Women in 11 Asian Countries: Findings From the PrEP APPEAL Cross-Sectional Online Survey.Journal of the International AIDS Society · 2026Article
- Perspectives on PrEP/PEP Integration in Telehealth Gender-Affirming Care: A Survey of Clients From a National Telehealth Platform.Open forum infectious diseases · 2026Article
- Preexposure Prophylaxis (PrEP) Communication Between PrEP-Eligible Latino Men: an Egocentric Analysis of Dyadic Characteristics and Behaviors.Prevention science : the official journal of the Society for Prevention Research · 2026Article
- HIV Preventive Measures' Adoption Among Men Who Have Sex With Men in West and Central Africa: A Scoping Review On Pre-exposure Prophylaxis and Condom Use.Journal of community health · 2026Review
- Social-Cognitive and Identity-Related Factors Promoting Pre-exposure Prophylaxis (PrEP) Uptake Among Bisexual Men.AIDS and behavior · 2026Article
- "There Needs To Be More People Sharing That Information Across the Nation": Opportunities to Promote HIV Pre-Exposure Prophylaxis Awareness and Uptake among People Releasing from Jail or Prison.Research square · 2026Article
- Preferences for mHealth Features to Support Engagement in the HIV Preexposure Prophylaxis Cascade Among Men Who Have Sex With Men in Peru: Cross-Sectional Online Survey.JMIR public health and surveillance · 2026Article
- Structural and Social Drivers of Pre-Exposure Prophylaxis (PrEP) Literacy Disparities Among Men who have Sex with Men in China: A PrEP Care Cascade Analysis.AIDS and behavior · 2026Article
- Impact of Post-exposure Prophylaxis on Pre-exposure Prophylaxis Initiation Among Men Who Have Sex with Men: A Nested Case-control Study.AIDS and behavior · 2026Article
- Correlates of PrEP Cascade Outcomes Among Immigrant Latino Men Who Have Sex with Men.AIDS and behavior · 2026Article
- Understanding PrEP Contemplation Among Black Women: Insights from a Qualitative Analysis.Journal of racial and ethnic health disparities · 2026Article
150 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesThe HIV care cascade provides milestones to track the progress of HIV-positive people from seroconversion through viral suppression. We propose a Motivational pre-exposure prophylaxis (PrEP) Cascade involving 5 stages based on the Transtheoretical Model of Change.
methodsWe analyzed data from 995 men in One Thousand Strong, a longitudinal study of a national panel of HIV-negative gay and bisexual men in the United States.
resultsNearly all (89%) participants were sexually active in the past 3 months and 65% met Centers for Disease Control criteria for PrEP candidacy. Of those identified as appropriate candidates, 53% were Precontemplative (stage 1; unwilling to take or believing they were inappropriate candidates for PrEP) and 23% were in Contemplation (stage 2; willing and self-identified as appropriate candidates). Only 11% were in PrEParation (stage 3; seeing PrEP as accessible and planning to initiate PrEP) and 4% were in PrEP Action (stage 4; prescribed PrEP). Although few of those who were identified as appropriate candidates were on PrEP, nearly all PrEP users (98%) reported adhering to 4 or more doses per week and most (72%) were returning for recommended quarterly medical visits, resulting in 9% of PrEP candidates reaching Maintenance and Adherence (stage 5).
conclusionsThe large majority of participants were appropriate candidates for PrEP, yet fewer than 1 in 10 were using and adherent to PrEP. These findings highlight the need for interventions tailored to address the unique barriers men face at each stage of the cascade, particularly at the earliest stages where the most dramatic losses were identified.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.