ArticleBMJ open2016
An online questionnaire survey of UK general practitioners' knowledge and management of familial hypercholesterolaemia.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Awareness and management of pediatric familial hypercholesterolemia: a Polish physician survey.Archives of medical science : AMS · 2025Article
- Primary care clinician engagement in implementing a machine-learning algorithm for targeted screening of familial hypercholesterolemia.American journal of preventive cardiology · 2024Article
- Unexpected gaps in knowledge of familial hypercholesterolaemia among Dutch general practitioners.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024Article
- Awareness and knowledge of heterozygous familial hypercholesterolemia among Serbian pediatricians.Frontiers in pediatrics · 2023Article
- A mixed methods study of the awareness and management of familial hypercholesterolaemia in Irish general practice.Frontiers in medicine · 2022Article
- Cascade Screening and Treatment Initiation in Young Adults with Heterozygous Familial Hypercholesterolemia.Journal of clinical medicine · 2021Article
- Screening for potential familial hypercholesterolaemia in general practice: an observational study on prevalence and management.BJGP open · 2021Article
- Validity and reliability of an adapted questionnaire measuring knowledge, awareness and practice regarding familial hypercholesterolaemia among primary care physicians in Malaysia.BMC cardiovascular disorders · 2021Article
- Genetic testing preferences and intentions in patients with clinically diagnosed familial hypercholesterolemia.Journal of genetic counseling · 2020Article
- Article
- Barriers to Early Diagnosis and Treatment of Familial Hypercholesterolemia: Current Perspectives on Improving Patient Care.Vascular health and risk management · 2020Review
- Barriers to the identification of familial hypercholesterolemia among primary care providers.Journal of community genetics · 2019Article
- Systematic Lab Knowledge Integration for Management of Lipid Excess in High-Risk Patients: Rationale and Design of the SKIM LEAN Project.Frontiers in big data · 2018Article
- Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveEarly diagnosis and treatment of heterozygous familial hypercholesterolaemia (HeFH) is known to be associated with reduced mortality from premature coronary artery disease, but HeFH remains underdiagnosed. This survey aims to determine knowledge and current management of HeFH in general practice.
settingAn online questionnaire was administered to general practitioners' (GPs') in the North West of England to assess their knowledge and management of HeFH.
participantsPractising GPs in the North West of England were contacted by email and invited to complete an online questionnaire. Recruitment discontinued when the target of 100 was reached. PRIMARY OUTCOME: An assessment of the knowledge and current management of HeFH in GPs.
results100 GP responses were analysed. Although only 39% considered themselves to have reasonable knowledge of HeFH, 89% knew that HeFH was a genetic disorder and 74% selected the correct lipid profile for diagnosing the condition. More than half (61%) were aware of current guidelines on HeFH. Gaps in knowledge were evident when only 30% correctly identified the prevalence of HeFH and half were not aware of the pattern of inheritance. Increased cardiovascular risk was underestimated by majority. 33% thought that they had HeFH patients in their practice confirming underdiagnosis of the condition. Statin therapy was recognised by 94% to be the right medication for treating HeFH. The majority (82%) regarded GPs to be the most effective healthcare professional for early recognition of HeFH.
conclusionsGPs have an above-average knowledge of familial hypercholesterolaemia (FH) and almost universally consider that they have a key role in the early recognition of undiagnosed HeFH patients in the community. However, there are gaps in awareness that need to be addressed to further enhance the care of FH in the community.
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