Evidence map›Paper›PMID 28186845›Full record

ArticleDento maxillo facial radiology2017

Image findings of bisphosphonate related osteonecrosis of jaws comparing with osteoradionecrosis.

Kenichi Obinata, Shinichi Shirai, Hitoshi Ito, Motoyasu Nakamura, Marco Carrozzo, Iain Macleod, Andrew Carr, Yutaka Yamazaki, Kanchu Tei

Abstract readComparative Study
In one paragraph

Article in Dento maxillo facial radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  10. Periosteal reaction of medication-related osteonecrosis of the jaw (MRONJ): clinical significance and changes during conservative therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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  12. Review
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  15. Sclerotic Lesions of the Jaw: A Pictorial Review.Journal of the Belgian Society of Radiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Kenichi Obinata1 Omni Dentix, Dartmouth, Sapporo, Hokkaido, Japan.
Shinichi Shirai1 Omni Dentix, Dartmouth, Sapporo, Hokkaido, Japan.
Hitoshi Ito1 Omni Dentix, Dartmouth, Sapporo, Hokkaido, Japan.
Motoyasu Nakamura2 Nakamura Dental Clinic, Sapporo, Hokkaido, Japan.
Marco Carrozzo3 Department of Oral Medicine, University of Newcastle upon Tyne, Newcastle upon Tyne, UK.
Iain Macleod4 Department of Dental Radiology, University of Newcastle upon Tyne, Newcastle upon Tyne, UK.
Andrew Carr4 Department of Dental Radiology, University of Newcastle upon Tyne, Newcastle upon Tyne, UK.
Yutaka Yamazaki5 Department of Oral Medicine, Center for Dental Clinics, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.
Kanchu Tei6 Department of Oral Surgery, Center for Dental Clinics, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.
Newcastle University · GBHokkaido University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate image characteristics of bisphosphonate-related osteonecrosis of the jaws (BRONJ) and compare these with osteoradionecrosis (ORN).

methods34 patients with BRONJ and 16 patients with ORN were included in this study. We investigated the CT and dental panoramic radiograph (DPR) images for osteolysis, osteosclerosis, sequestration, periosteal reaction, pathological fracture and spread of soft tissue inflammation around the jaws.

resultsOsteolysis, osteosclerosis, sequestration and spread of soft tissue inflammation around the jaws were common radiological features in both BRONJ and ORN. Osteolysis and spreading of soft tissue inflammation around the jaws were predominant in ORN, and by contrast osteosclerosis was predominant in BRONJ. Periosteal reaction was established in 15 of the 34 BRONJ cases, but none in the ORN cases. Pathological fractures were observed in 6 of 16 ORN cases, but none in BRONJ cases. CT was better for detection than DPR for osteolysis, osteosclerosis, sequestration and periosteal reactions.

conclusionsImage findings of BRONJ were characterized as a severe sclerotic change combined with osteolysis, sequestration, periosteal reaction and spread of soft tissue inflammation around the jaws.

Indexed as

AdultAgedAged, 80 and overBisphosphonate-Associated Osteonecrosis of the JawFemaleHumansMaleMiddle AgedOsteoradionecrosisRadiography, PanoramicTomography, X-Ray Computedbisphosphonate-related osteonecrosis of the jawCTosteoradionecrosispanoramic radiography

Identifiers

PMID28186845
PMCPMC5595031
OpenAlexW2587114150

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.