Evidence map›Paper›PMID 28186844›Full record

Observational studyDento maxillo facial radiology2017

Prevalence of calcified carotid artery atheromas on panoramic images of older men with gout: a descriptive retrospective study.

Arthur H Friedlander, Lindsay L Graves, Shannon G Grabich, Nona Aghazadehsanai, Tina I Chang

Abstract readObservational Study
In one paragraph

Observational study in Dento maxillo facial radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Carotid Artery Calcifications on Panoramic Radiographs.International journal of environmental research and public health · 2022
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Arthur H Friedlander1 Graduate Medical Education Service, Veterans Affairs, Greater Los Angeles Healthcare System, Los Angeles, CA, USA.
Lindsay L Graves4 Dental Service, Veterans Affairs, Greater Los Angeles Healthcare System.
Shannon G Grabich5 Research Service, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Nona Aghazadehsanai4 Dental Service, Veterans Affairs, Greater Los Angeles Healthcare System.
Tina I Chang3 UCLA Dental School, Los Angeles, CA, USA.
VA Greater Los Angeles Healthcare System · USRonald Reagan UCLA Medical Center · USUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesGiven the enhanced risk of ischaemic stroke resulting from the direct effects of hyperuricaemia on vascular plaque formation seen among older males with gout, we sought to determine the prevalence of calcified carotid artery atheromas (CCAAs) on their panoramic images (PIs).

methodsMedical record librarians identified all male patients over 45 years, who had a diagnosis of gout and a PI incidentally obtained between 2000 and 2015. The prevalence rate of CCAA on technically appropriate images was determined, as were these patients' atherogenic risk profiles including: age, body mass index, hypertension and dyslipidaemia. Comparisons of atherogenic risk factors were made between this cohort and those without CCAA.

resultsOf the 531 patients with gout, 163 patients were adjudicated to be CCAA+ (the panoramic image demonstrates a calcified carotid artery atheroma). Logistic regression analysis demonstrated that a comorbid diagnosis of diabetes mellitus or dyslipidaemia, or advancing age was determinant in differentiating patients who were CCAA+ vs those who were CCAA- (the panoramic image does not demonstrate a calcified carotid artery atheroma).

conclusionsCCAAs often herald an ischaemic stroke and may be seen on the PIs of patients with gout, especially those with increased age, dyslipidaemia or diabetes. Thus, dentists must be uniquely vigilant in detecting these lesions when evaluating the images of all patients with gout, especially those with additional positive risk factors.

Indexed as

AgedCarotid Artery DiseasesGoutHumansIncidenceMaleMiddle AgedPlaque, AtheroscleroticPrevalenceRetrospective StudiesRisk FactorsUnited Statesatherosclerosiscarotid arterygoutpanoramic images

Identifiers

PMID28186844
PMCPMC5595035
OpenAlexW2586374077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.