Evidence map›Paper›PMID 28186182›Full record

ArticleScientific reports2017

Topological determinants of self-sustained activity in a simple model of excitable dynamics on graphs.

Christoph Fretter, Annick Lesne, Claus C Hilgetag, Marc-Thorsten Hütt

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
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  4. Link-usage asymmetry and collective patterns emerging from rich-club organization of complex networks.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Christoph FretterDepartment of Life Sciences and Chemistry, Jacobs University Bremen, D-28759 Bremen, Germany.
Annick LesneLPTMC, CNRS, UMR 7600, UPMC-Paris 6, Sorbonne Universités, 4 place Jussieu, F-75252, Paris, France.
Claus C HilgetagDepartment of Computational Neuroscience, Universitätsklinikum Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Marc-Thorsten HüttDepartment of Life Sciences and Chemistry, Jacobs University Bremen, D-28759 Bremen, Germany.
Boston University · USCentre National de la Recherche Scientifique · FRConstructor University · DEUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simple models of excitable dynamics on graphs are an efficient framework for studying the interplay between network topology and dynamics. This topic is of practical relevance to diverse fields, ranging from neuroscience to engineering. Here we analyze how a single excitation propagates through a random network as a function of the excitation threshold, that is, the relative amount of activity in the neighborhood required for the excitation of a node. We observe that two sharp transitions delineate a region of sustained activity. Using analytical considerations and numerical simulation, we show that these transitions originate from the presence of barriers to propagation and the excitation of topological cycles, respectively, and can be predicted from the network topology. Our findings are interpreted in the context of network reverberations and self-sustained activity in neural systems, which is a question of long-standing interest in computational neuroscience.

Identifiers

PMID28186182
PMCPMC5301238
OpenAlexW2963515241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.