Evidence map›Paper›PMID 28186087›Full record

ArticleCancer gene therapy2017

Baculovirus directly activates murine NK cells via TLR9.

T Moriyama, T Suzuki, M O Chang, M Kitajima, H Takaku

Abstract read
PubMed Publisher
In one paragraph

Article in Cancer gene therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

T MoriyamaDepartment of Life and Environmental Sciences, Chiba Institute of Technology, Narashino, Chiba, Japan.
T SuzukiDepartment of Life and Environmental Sciences, Chiba Institute of Technology, Narashino, Chiba, Japan.
M O ChangDepartment of Life and Environmental Sciences, Chiba Institute of Technology, Narashino, Chiba, Japan.
M KitajimaDepartment of Immunology and Pathology, Research Institute National Center for Global Health and Medicine, Ichikawa, Chiba, Japan.
H TakakuResearch Institute, Chiba Institute of Technology, Narashino, Chiba, Japan.
Chiba Institute of Technology · JPNational Center for Global Health and Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of natural killer (NK) cells in innate immune responses against tumors or viral infections enhances the appeal of NK cell-based immunotherapeutic approaches. We have recently reported that baculovirus (BV)-infected dendritic cells (DCs; BV-DCs) induce antitumor immunity against established tumors in mice. These antitumor effects were CD8

Indexed as

AnimalsAntigens, CDAntigens, Differentiation, T-LymphocyteBaculoviridaeCD69 AntigensFemaleImmunotherapyInterferon-gammaKiller Cells, NaturalLectins, C-TypeLymphocyte ActivationMiceMice, KnockoutNeoplasmsToll-Like Receptor 9Antigens, CDAntigens, Differentiation, T-LymphocyteCD69 AntigensIFNG protein, mouseInterferon-gammaLectins, C-TypeTlr9 protein, mouseToll-Like Receptor 9

Identifiers

PMID28186087
OpenAlexW2587403767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.