Evidence map›Paper›PMID 28185108›Full record

Observational studyInternational urology and nephrology2017

Low prognostic nutritional index associated with cardiovascular disease mortality in incident peritoneal dialysis patients.

Fenfen Peng, Wenjing Chen, Weidong Zhou, Peilin Li, Hongxin Niu, Yihua Chen, Yan Zhu, Haibo Long

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fenfen PengDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Wenjing ChenDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Weidong ZhouDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Peilin LiDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Hongxin NiuDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Yihua ChenDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Yan ZhuDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China.
Haibo LongDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China. Longhb1966@163.com.
Southern Medical University · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe prognostic nutritional index (PNI), a variable based on serum albumin concentration and total lymphocyte count in peripheral blood, is reported as a predictor of mortality in a variety of malignant tumor population. This study is aimed to evaluate whether PNI has prognostic value in patients on peritoneal dialysis (PD).

methodsThis was a single-center, retrospective observational cohort study conducted in incident PD patients from January 1, 2006 to June 30, 2014, and followed until June 30, 2015. The associations of PNI levels with mortality were evaluated by Kaplan-Meier method and Cox proportional hazards models.

resultsA total of 345 patients were included in this study. Median PNI level at baseline was 40.7 (range: 18.8-75.5) for all patients. During follow-up, 59 (17.1%) died during follow-up, among which 31 (52.5%) were due to cardiovascular diseases (CVD). In crude analysis, the patients with low PNI had a significant increase risk of CVD and all-cause mortality [hazard ratio (HR) 3.07, 95% confidence interval (CI) 1.51-6.25 and HR 2.18, 95% CI 1.28-3.72, respectively)]. After adjusting age, Davies comorbidity score, hemoglobin and leukocytes, the patients with low PNI still had a significant increased risk of CVD mortality (HR 2.37, 95% CI 1.10-5.12). However, there was no significant difference in risk of all-cause mortality (HR 1.72, 95% CI 0.97-3.06).

conclusionsLow PNI at initiation of PD was independently associated with an increased CVD mortality.

Indexed as

Nutritional StatusPeritoneal DialysisAdolescentAdultAgedCardiovascular DiseasesCause of DeathFemaleFollow-Up StudiesHumansKaplan-Meier EstimateKidney Failure, ChronicMaleMiddle AgedPrognosisProportional Hazards ModelsCardiovascular diseaseMortalityPeritoneal dialysisPrognostic nutritional index

Identifiers

PMID28185108
OpenAlexW2586583233

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.